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蒙特卡罗方法得出的关于水、铝和铜中50 keV至25 MeV光子束的剂量-比释动能-碰撞比释动能相互关系的见解。

Monte-Carlo-derived insights into dose-kerma-collision kerma inter-relationships for 50 keV-25 MeV photon beams in water, aluminum and copper.

作者信息

Kumar Sudhir, Deshpande Deepak D, Nahum Alan E

机构信息

Department of Physics, Clatterbridge Cancer Centre, Bebington, CH63 4JY, UK. Department of Physics, University of Liverpool, Liverpool L69 7ZE, UK. Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, CT & CRS building, Anushaktinagar, Mumbai-400094, India. Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai-400 094, India.

出版信息

Phys Med Biol. 2015 Jan 21;60(2):501-19. doi: 10.1088/0031-9155/60/2/501. Epub 2014 Dec 30.

DOI:10.1088/0031-9155/60/2/501
PMID:25548933
Abstract

The relationships between D, K and Kcol are of fundamental importance in radiation dosimetry. These relationships are critically influenced by secondary electron transport, which makes Monte-Carlo (MC) simulation indispensable; we have used MC codes DOSRZnrc and FLURZnrc. Computations of the ratios D/K and D/Kcol in three materials (water, aluminum and copper) for large field sizes with energies from 50 keV to 25 MeV (including 6-15 MV) are presented. Beyond the depth of maximum dose D/K is almost always less than or equal to unity and D/Kcol greater than unity, and these ratios are virtually constant with increasing depth. The difference between K and Kcol increases with energy and with the atomic number of the irradiated materials. D/K in 'sub-equilibrium' small megavoltage photon fields decreases rapidly with decreasing field size. A simple analytical expression for X̅, the distance 'upstream' from a given voxel to the mean origin of the secondary electrons depositing their energy in this voxel, is proposed: X̅(emp) ≈ 0.5R(csda)(E̅(0)), where E̅(0) is the mean initial secondary electron energy. These X̅(emp) agree well with 'exact' MC-derived values for photon energies from 5-25 MeV for water and aluminum. An analytical expression for D/K is also presented and evaluated for 50 keV-25 MeV photons in the three materials, showing close agreement with the MC-derived values.

摘要

在辐射剂量学中,D、K和Kcol之间的关系至关重要。这些关系受到次级电子输运的严重影响,这使得蒙特卡罗(MC)模拟不可或缺;我们使用了MC代码DOSRZnrc和FLURZnrc。本文给出了在50 keV至25 MeV(包括6 - 15 MV)能量范围内,三种材料(水、铝和铜)大野尺寸下D/K和D/Kcol比值的计算结果。在最大剂量深度之后,D/K几乎总是小于或等于1,而D/Kcol大于1,并且这些比值随着深度增加实际上是恒定的。K和Kcol之间的差异随着能量以及被辐照材料的原子序数增加而增大。在“次平衡”小兆伏光子场中,D/K随着场尺寸减小而迅速降低。提出了一个关于X̅的简单解析表达式,X̅是从给定体素到在该体素中沉积其能量的次级电子的平均起源点的“上游”距离:X̅(emp) ≈ 0.5R(csda)(E̅(0)),其中E̅(0)是次级电子的平均初始能量。对于水和铝,这些X̅(emp)与5 - 25 MeV光子能量下由MC得出的“精确”值吻合良好。还给出了D/K的解析表达式,并针对三种材料中50 keV - 25 MeV的光子进行了评估,结果显示与MC得出的值非常吻合。

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