Department of Allergy and Immunology, Ajou University School of Medicine, Suwon, Korea.
Hallym University Sacred Heart Hospital, Pulmonary & Allergy Center, Anyang, Korea.
Allergy Asthma Immunol Res. 2015 Jan;7(1):30-6. doi: 10.4168/aair.2015.7.1.30. Epub 2014 Jul 16.
Smoking has detrimental effects on asthma symptom control and response to treatment and is prevalent among asthma patients in South Korea. The aim of this study is to determine the prevalence of smoking among asthma patients in South Korea and to compare the medication regimens of asthma patients who do and do not smoke.
A cross-sectional survey was conducted from August 2010 to January 2011. Participating physicians (N=25) recorded demographic and clinical data on all asthma patients presenting during the study period (N=2,032), and then recruited a subset of patients (N=500) for the survey such that half were self-reported current smokers. Recruited patients were between the ages of 18 and 60.
Among presenting asthma patients, 17.3% were current smokers, 19.2% were former smokers, and 63.5% had never smoked. Within the analyzable study population (N=471), 212 patients reported smoking currently, 79 smoking formerly, and 180 never smoking. Among current and former smokers, 79.7% and 81.0%, respectively, were men, while women represented 80.5% of patients who had never smoked. Agreement was strong between physician-determined smoking status and patient-reported smoking status (κ=0.82; P<0.001). However, asthma medication regimens examined according to GINA treatment steps did not differ by smoking status. In addition, mean quality of life scores and level of asthma control did not differ by smoking status.
In South Korea, physicians are well aware of the smoking status of their patients. However, smoking status did not affect the prescribed medication regimens of this population of asthma patients.
吸烟对哮喘症状控制和治疗反应有不利影响,在韩国哮喘患者中较为普遍。本研究旨在确定韩国哮喘患者的吸烟率,并比较吸烟和不吸烟哮喘患者的药物治疗方案。
本研究采用横断面调查,于 2010 年 8 月至 2011 年 1 月进行。参与研究的医生(N=25)记录了所有在研究期间就诊的哮喘患者(N=2032)的人口统计学和临床数据,并招募了一部分患者(N=500)进行调查,其中一半为自我报告的现吸烟患者。招募的患者年龄在 18 至 60 岁之间。
在就诊的哮喘患者中,17.3%为现吸烟患者,19.2%为曾经吸烟患者,63.5%从未吸烟。在可分析的研究人群(N=471)中,212 名患者报告目前吸烟,79 名患者报告曾经吸烟,180 名患者从未吸烟。在现吸烟和曾经吸烟的患者中,分别有 79.7%和 81.0%为男性,而从未吸烟的患者中女性占 80.5%。医生确定的吸烟状况与患者报告的吸烟状况之间具有高度一致性(κ=0.82;P<0.001)。然而,根据 GINA 治疗步骤检查的哮喘药物治疗方案并未因吸烟状况而有所不同。此外,吸烟状况对生活质量评分和哮喘控制水平均无影响。
在韩国,医生对患者的吸烟状况有较好的了解。然而,吸烟状况并未影响该人群哮喘患者的处方药物治疗方案。