Cielo Christopher M, Marcus Carole L
9NW50, Main Hospital, The Children's Hospital of Philadelphia, 34(th) and Civic Center Boulevard, Philadelphia, PA 19104.
Paediatr Respir Rev. 2015 Jun;16(3):189-96. doi: 10.1016/j.prrv.2014.11.003. Epub 2014 Dec 3.
Obstructive sleep apnoea syndrome (OSAS) is common in children. Craniofacial anomalies such as cleft palate are among the most common congenital conditions. Children with a variety of craniofacial conditions, including cleft palate, micrognathia, craniosynostosis, and midface hypoplasia are at increased risk for OSAS. Available evidence, which is largely limited to surgical case series and retrospective studies, suggests that OSAS can be successfully managed in these children through both surgical and non-surgical techniques. Prospective studies using larger cohorts of patients and including polysomnograms are needed to better understand the risk factors for this patient population and the efficacy of treatment options for OSAS and their underlying conditions.
阻塞性睡眠呼吸暂停综合征(OSAS)在儿童中很常见。腭裂等颅面畸形是最常见的先天性疾病之一。患有各种颅面疾病的儿童,包括腭裂、小颌畸形、颅缝早闭和面中部发育不全,患OSAS的风险增加。现有证据在很大程度上仅限于手术病例系列和回顾性研究,表明通过手术和非手术技术可以成功治疗这些儿童的OSAS。需要使用更大的患者队列并包括多导睡眠图的前瞻性研究,以更好地了解该患者群体的危险因素以及OSAS及其潜在疾病的治疗方案的疗效。