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对爱泼斯坦-巴尔病毒质粒复制起点(oriP)的分析揭示了一个跨越3'二聚体的核小体缺失区域。

Analysis of the Epstein-Barr virus origin of plasmid replication (oriP) reveals an area of nucleosome sparing that spans the 3' dyad.

作者信息

Sexton C J, Pagano J S

机构信息

Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599-7295.

出版信息

J Virol. 1989 Dec;63(12):5505-8. doi: 10.1128/JVI.63.12.5505-5508.1989.

Abstract

The Epstein-Barr virus oriP, when examined with the use of in vitro nucleosome reconstitution, was found to exhibit a partial sparing of nucleosome assembly within the 3' dyad. Analysis of the homologous region containing the origin of replication of herpesvirus papio disclosed that sparing of nucleosome assembly was conserved between these two related viruses.

摘要

在使用体外核小体重组进行检测时,发现爱泼斯坦-巴尔病毒oriP在3'二联体区域内表现出核小体组装的部分保留。对包含疱疹病毒狒狒复制起点的同源区域进行分析后发现,这两种相关病毒在核小体组装保留方面具有保守性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1288/251226/1e4cb97fdc38/jvirol00079-0528-a.jpg

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