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对爱泼斯坦-巴尔病毒质粒复制起点(oriP)的分析揭示了一个跨越3'二聚体的核小体缺失区域。

Analysis of the Epstein-Barr virus origin of plasmid replication (oriP) reveals an area of nucleosome sparing that spans the 3' dyad.

作者信息

Sexton C J, Pagano J S

机构信息

Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599-7295.

出版信息

J Virol. 1989 Dec;63(12):5505-8. doi: 10.1128/JVI.63.12.5505-5508.1989.

DOI:10.1128/JVI.63.12.5505-5508.1989
PMID:2555570
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC251226/
Abstract

The Epstein-Barr virus oriP, when examined with the use of in vitro nucleosome reconstitution, was found to exhibit a partial sparing of nucleosome assembly within the 3' dyad. Analysis of the homologous region containing the origin of replication of herpesvirus papio disclosed that sparing of nucleosome assembly was conserved between these two related viruses.

摘要

在使用体外核小体重组进行检测时,发现爱泼斯坦-巴尔病毒oriP在3'二联体区域内表现出核小体组装的部分保留。对包含疱疹病毒狒狒复制起点的同源区域进行分析后发现,这两种相关病毒在核小体组装保留方面具有保守性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1288/251226/1e4cb97fdc38/jvirol00079-0528-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1288/251226/1e4cb97fdc38/jvirol00079-0528-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1288/251226/1e4cb97fdc38/jvirol00079-0528-a.jpg

相似文献

1
Analysis of the Epstein-Barr virus origin of plasmid replication (oriP) reveals an area of nucleosome sparing that spans the 3' dyad.对爱泼斯坦-巴尔病毒质粒复制起点(oriP)的分析揭示了一个跨越3'二聚体的核小体缺失区域。
J Virol. 1989 Dec;63(12):5505-8. doi: 10.1128/JVI.63.12.5505-5508.1989.
2
The Epstein-Barr virus origin of plasmid replication, oriP, contains both the initiation and termination sites of DNA replication.爱泼斯坦-巴尔病毒质粒复制起点oriP包含DNA复制的起始和终止位点。
Cell. 1989 Aug 11;58(3):527-35. doi: 10.1016/0092-8674(89)90433-9.
3
Epstein-Barr nuclear antigen 1 binds and destabilizes nucleosomes at the viral origin of latent DNA replication.爱泼斯坦-巴尔核抗原1在潜伏性DNA复制的病毒起源处结合并使核小体不稳定。
Nucleic Acids Res. 2001 Sep 1;29(17):3520-8. doi: 10.1093/nar/29.17.3520.
4
Single-stranded structures are present within plasmids containing the Epstein-Barr virus latent origin of replication.在含有爱泼斯坦-巴尔病毒潜伏性复制起点的质粒中存在单链结构。
J Virol. 1991 Feb;65(2):677-86. doi: 10.1128/JVI.65.2.677-686.1991.
5
Plasmid maintenance of derivatives of oriP of Epstein-Barr virus.爱泼斯坦-巴尔病毒oriP衍生物的质粒维持
J Virol. 1995 Feb;69(2):1280-3. doi: 10.1128/JVI.69.2.1280-1283.1995.
6
Rep*: a viral element that can partially replace the origin of plasmid DNA synthesis of Epstein-Barr virus.Rep*:一种病毒元件,可部分替代爱泼斯坦-巴尔病毒质粒DNA合成的起始位点。
J Virol. 1998 Jun;72(6):4657-66. doi: 10.1128/JVI.72.6.4657-4666.1998.
7
Herpesvirus papio contains a plasmid origin of replication that acts in cis interspecies with an Epstein-Barr virus trans-acting function.狒狒疱疹病毒含有一个质粒复制起点,该起点在种间与爱泼斯坦-巴尔病毒反式作用功能顺式作用。
J Virol. 1986 Dec;60(3):1159-62. doi: 10.1128/JVI.60.3.1159-1162.1986.
8
Plasmid origin of replication of Epstein-Barr virus, oriP, does not limit replication in cis.爱泼斯坦-巴尔病毒的质粒复制起点oriP并不在顺式作用中限制复制。
Mol Biol Med. 1988 Apr;5(2):85-94.
9
Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus.爱泼斯坦-巴尔核抗原1介导爱泼斯坦-巴尔病毒潜伏复制起点内的一个DNA环。
Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10875-9. doi: 10.1073/pnas.88.23.10875.
10
Cell cycle regulation of chromatin at an origin of DNA replication.DNA复制起点处染色质的细胞周期调控。
EMBO J. 2005 Apr 6;24(7):1406-17. doi: 10.1038/sj.emboj.7600609. Epub 2005 Mar 17.

引用本文的文献

1
Epstein-Barr nuclear antigen 1 (EBNA1)-dependent recruitment of origin recognition complex (Orc) on oriP of Epstein-Barr virus with purified proteins: stimulation by Cdc6 through its direct interaction with EBNA1. Epstein-Barr 核抗原 1(EBNA1)依赖性募集起始识别复合物(Orc)在 Epstein-Barr 病毒 oriP 上的纯蛋白:通过 Cdc6 与其与 EBNA1 的直接相互作用的刺激。
J Biol Chem. 2012 Jul 6;287(28):23977-94. doi: 10.1074/jbc.M112.368456. Epub 2012 May 14.
2
cdc2/cyclin B1-dependent phosphorylation of EBNA2 at Ser243 regulates its function in mitosis.EBNA2在丝氨酸243处的细胞周期蛋白依赖性激酶2/细胞周期蛋白B1磷酸化调节其在有丝分裂中的功能。
J Virol. 2006 Feb;80(4):2045-50. doi: 10.1128/JVI.80.4.2045-2050.2006.
3

本文引用的文献

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Effect of the B--Z transition in poly(dG-m5dC) . poly(dG-m5dC) on nucleosome formation.聚(dG-m5dC)·聚(dG-m5dC)中B-Z转变对核小体形成的影响。
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Nucleic Acids Res. 2001 Sep 1;29(17):3520-8. doi: 10.1093/nar/29.17.3520.
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Plasmid origin of replication of herpesvirus papio: DNA sequence and enhancer function.狒狒疱疹病毒的质粒复制起点:DNA序列及增强子功能
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Single-stranded structures are present within plasmids containing the Epstein-Barr virus latent origin of replication.在含有爱泼斯坦-巴尔病毒潜伏性复制起点的质粒中存在单链结构。
J Virol. 1991 Feb;65(2):677-86. doi: 10.1128/JVI.65.2.677-686.1991.
来自爱泼斯坦-巴尔病毒基因组的一个顺式作用元件,其可使重组质粒在潜伏感染细胞中稳定复制。
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4
Replication of Epstein-Barr virus DNA in lymphoblastoid cells treated for extended periods with acyclovir.爱泼斯坦-巴尔病毒DNA在长期用阿昔洛韦处理的淋巴母细胞中的复制。
Am J Med. 1982 Jul 20;73(1A):77-81. doi: 10.1016/0002-9343(82)90068-7.
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Colinearity between the DNAs of Epstein-Barr virus and herpesvirus papio.爱泼斯坦-巴尔病毒与狒狒疱疹病毒DNA之间的共线性
J Virol. 1981 Feb;37(2):821-6. doi: 10.1128/JVI.37.2.821-826.1981.
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Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA.在SV40染色质中,复制起点与晚期前导RNA编码区域之间的一部分区域不存在核小体。
Cell. 1980 May;20(1):65-73. doi: 10.1016/0092-8674(80)90235-4.
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A nucleosome-free region in SV40 minichromosomes.猴病毒40型(SV40)微型染色体中的无核小体区域。
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Random protection of single cut restriction endonuclease sites in SV40 mini-chromosomes assembled in vitro.体外组装的SV40微型染色体中单个切割限制内切酶位点的随机保护。
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Phasing of nucleosomes in SV40 chromatin reconstituted in vitro.体外重构的SV40染色质中核小体的相位分析。
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Nucleic Acids Res. 1980 Feb 11;8(3):555-66. doi: 10.1093/nar/8.3.555.