狒狒疱疹病毒含有一个质粒复制起点，该起点在种间与爱泼斯坦-巴尔病毒反式作用功能顺式作用。
Herpesvirus papio contains a plasmid origin of replication that acts in cis interspecies with an Epstein-Barr virus trans-acting function.
作者信息
Pesano R L, Pagano J S
出版信息
J Virol. 1986 Dec;60(3):1159-62. doi: 10.1128/JVI.60.3.1159-1162.1986.
Herpesvirus papio (HVP) and Epstein-Barr virus (EBV) are closely related biologically and biochemically; lymphoblastoid cells infected with either virus contain episomal viral DNA. The putative origin of replication for EBV plasmids (oriP) has been assigned to a 1,790-base-pair fragment (cis) in the short unique region of the genome which requires a viral function supplied in trans from elsewhere in the genome (J. Yates, N. Warren, D. Reisman, and B. Sugden, Proc. Natl. Acad. Sci. USA 81:3806-3810, 1984). We report here the identification of the putative origin of replication (cis) in HVP; we assigned it to the HVP EcoRI K fragment. The results indicate that the HVP replication process requires both a cis and a trans-acting function, analogous to that found in EBV.
狒狒疱疹病毒（HVP）和爱泼斯坦-巴尔病毒（EBV）在生物学和生物化学上密切相关；感染这两种病毒的淋巴母细胞都含有游离的病毒DNA。EBV质粒的假定复制起点（oriP）已被定位到基因组短独特区域中的一个1790碱基对的片段（顺式作用元件），该片段需要从基因组其他位置反式提供的病毒功能（J. 耶茨、N. 沃伦、D. 赖斯曼和B. 萨格登，《美国国家科学院院刊》81:3806 - 3810，1984年）。我们在此报告HVP假定复制起点（顺式作用元件）的鉴定；我们将其定位到HVP EcoRI K片段。结果表明，HVP复制过程需要顺式和反式作用功能，这与在EBV中发现的情况类似。
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