a SCIENT - Research Center for Instrumental Analysis (by S.C. CROMATEC_PLUS S.R.L.) , Bucharest , Romania.
Crit Rev Anal Chem. 2015;45(2):156-65. doi: 10.1080/10408347.2014.904733.
This review provides a brief background to the application of infrared spectroscopy, including Fourier transform-infrared spectroscopy, in biological fluids. It is not meant to be complete or exhaustive but to provide the reader with sufficient background for selected applications in cancer diagnostics. Fourier transform-infrared spectroscopy (FT-IR) is a fast and nondestructive analytical method. The infrared spectrum of a mixture serves as the basis to quantitate its constituents, and a number of common clinical chemistry tests have proven to be feasible using this approach. This review focuses on biomedical FT-IR applications, published in the period 2009-2013, used for early detection of cancer through qualitative and quantitative analysis.
这篇综述简要介绍了红外光谱，包括傅里叶变换红外光谱，在生物流体中的应用。它并不是要完整或详尽的，而是为读者提供足够的背景知识，以便在癌症诊断的选定应用中使用。傅里叶变换红外光谱（FT-IR）是一种快速、无损的分析方法。混合物的红外光谱可作为定量其成分的基础，并且已经证明许多常见的临床化学测试都可以通过这种方法来实现。本综述重点介绍了 2009-2013 年间发表的用于通过定性和定量分析早期检测癌症的生物医学 FT-IR 应用。
