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吸烟与饮酒的实时模式:一项针对危险饮酒吸烟者的观察性研究方案

Real-time patterns of smoking and alcohol use: an observational study protocol of risky-drinking smokers.

作者信息

Cohn Amy, Brandon Thomas, Armeli Stephen, Ehlke Sarah, Bowers Molly

机构信息

Schroeder Institute, Washington DC, USA.

Moffitt Cancer Center, University of South Florida, Tampa, Florida, USA.

出版信息

BMJ Open. 2015 Jan 6;5(1):e007046. doi: 10.1136/bmjopen-2014-007046.

Abstract

INTRODUCTION

Despite the strong relationship between smoking and health-related consequences, very few smokers quit. Heavy drinking is a significant risk factor for health consequences, and is implicated in persistent smoking and less success at quitting smoking. Self-efficacy (SE) to abstain from smoking is an important determinant of smoking outcomes and may link alcohol use to poor quit rates. Even though research has demonstrated a strong association between drinking and smoking, and the multiplicative effect of these substances on cancer-related, heavy-drinking smokers has been largely ignored in the literature. Further, research has not taken advantage of innovative methods, such as ecological momentary assessment, to capture the impact of daily factors on smoking cessation outcomes in this particular group. The proposed study identifies daily changing factors that impede or promote SE and future smoking cessation efforts in risky-drinking smokers.

METHODS AND ANALYSIS

This is an observational study of 84 regular smokers (≥10 cigarettes per day) who drink at risky levels, report a desire to quit in the next 6 months, and show no evidence of psychiatric disturbance, severe history of alcohol withdrawal or drug dependence (excluding nicotine and caffeine). Participants report on their smoking, alcohol consumption and SE related to smoking twice a day for 28 days using interactive voice response (IVR) surveys. Multilevel regression and path models will examine within-person daily associations among drinking, smoking and SE, and how these variables predict the likelihood of future smoking behaviour at 1 and 6 months follow-up.

ETHICS AND DISSEMINATION

This protocol was approved by an accredited Institutional Review Board. The findings will help us understand the factors that promote or impede smoking cessation among a high-risk group of smokers (heavy-drinking smokers) and will be disseminated through peer-reviewed journal articles and presentations at national conferences.

摘要

引言

尽管吸烟与健康后果之间存在密切关系,但很少有吸烟者戒烟。大量饮酒是健康后果的一个重要风险因素,与持续吸烟和戒烟成功率较低有关。戒烟的自我效能感是吸烟结果的一个重要决定因素,可能将饮酒与低戒烟率联系起来。尽管研究表明饮酒与吸烟之间存在密切关联,但这些物质对癌症相关的大量饮酒吸烟者的综合影响在文献中基本被忽视。此外,研究尚未利用创新方法,如生态瞬时评估,来捕捉日常因素对这一特定群体戒烟结果的影响。拟议的研究确定了阻碍或促进高危饮酒吸烟者自我效能感及未来戒烟努力的日常变化因素。

方法与分析

这是一项针对84名规律吸烟者(每天≥10支香烟)的观察性研究,这些吸烟者饮酒量处于高危水平,报告称希望在未来6个月内戒烟,且无精神障碍、严重酒精戒断史或药物依赖(不包括尼古丁和咖啡因)的证据。参与者通过交互式语音应答(IVR)调查,在28天内每天报告两次其吸烟、饮酒情况以及与吸烟相关的自我效能感。多层次回归和路径模型将研究饮酒、吸烟和自我效能感之间的个体内日常关联,以及这些变量如何预测在1个月和6个月随访时未来吸烟行为的可能性。

伦理与传播

本方案已获得认可的机构审查委员会的批准。研究结果将有助于我们了解促进或阻碍高危吸烟者群体(大量饮酒吸烟者)戒烟的因素,并将通过同行评审的期刊文章和在全国会议上的报告进行传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb1e/4289730/3847d3f58443/bmjopen2014007046f01.jpg

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