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照顾过敏性鼻炎患者。

Caring for patients with allergic rhinitis.

作者信息

Hayden Mary Lou, Womack Catherine R

机构信息

Virginia Adult/Pediatric Allergy and Asthma, Virginia, USA.

出版信息

J Am Acad Nurse Pract. 2007 Jun;19(6):290-8. doi: 10.1111/j.1745-7599.2007.00228.x.

Abstract

PURPOSE

Allergic rhinitis (AR) affects up to 40 million Americans, with an estimated cost of $2.7 billion per annum. This review discusses several therapeutic options that reduce the symptoms of AR, including allergen avoidance, antihistamines, intranasal corticosteroids (INS), leukotriene receptor antagonists, and immunotherapy.

DATA SOURCES

The articles included in this review were retrieved by a search of Medline literature on the subjects of AR, antihistamines, INS, leukotriene antagonists, and immunotherapy, as well as current published guidelines for the treatment of AR.

CONCLUSIONS

Allergen avoidance is recommended for all patients prior to pharmacologic therapy. Oral and nasal H(1)-antihistamines are recommended to alleviate the mild and intermittent symptoms of AR, and INS are recommended as the first-line treatment choice for mild persistent and more moderate-to-severe persistent AR.

IMPLICATIONS FOR PRACTICE

There are a number of different types of therapy for the management of AR; with so many options available, successful tailoring of treatment to suit individual requirements is realistically achievable.

摘要

目的

变应性鼻炎(AR)影响多达4000万美国人,估计每年花费27亿美元。本综述讨论了几种减轻AR症状的治疗选择,包括避免接触变应原、使用抗组胺药、鼻用糖皮质激素(INS)、白三烯受体拮抗剂和免疫疗法。

数据来源

本综述纳入的文章通过检索Medline文献获得,这些文献涉及AR、抗组胺药、INS、白三烯拮抗剂和免疫疗法等主题,以及当前已发表的AR治疗指南。

结论

在进行药物治疗之前,建议所有患者避免接触变应原。推荐使用口服和鼻用H(1)抗组胺药来缓解AR的轻度和间歇性症状,INS被推荐作为轻度持续性和中重度持续性AR的一线治疗选择。

对实践的启示

有多种不同类型的疗法可用于管理AR;有这么多选择,根据个体需求成功定制治疗方案在现实中是可以实现的。

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