Pinna Federica, Sanna Lucia, Carpiniello Bernardo
Department of Public Health, Clinical and Molecular Medicine - Unit of Psychiatry, University of Cagliari, Cagliari, Italy.
Psychol Res Behav Manag. 2014 Dec 22;8:1-15. doi: 10.2147/PRBM.S52656. eCollection 2015.
A high percentage of individuals affected by eating disorders (ED) achieve incomplete recovery following treatment. In an attempt to improve treatment outcome, it is crucial that predictors of outcome are identified, and personalized care approaches established in line with new treatment targets, thus facilitating patient access to evidence-based treatments. Among the psychological factors proposed as predictors of outcome in ED, alexithymia is of outstanding interest. The objective of this paper is to undertake a systematic review of the literature relating to alexithymia, specifically in terms of the implications for treatment of ED. In particular, issues concerning the role of alexithymia as a predictor of outcome and as a factor to be taken into account in the choice of treatment will be addressed. The effect of treatments on alexithymia will also be considered. A search of all relevant literature published in English using PubMed, PsycINFO, and Scopus databases was carried out on the basis of the following keywords: alexithymia, anorexia nervosa, bulimia nervosa, eating disorders, and treatment; no time limits were imposed. Despite the clinical relevance of alexithymia, the number of studies published on the above cited aspects is somewhat limited, and these studies are largely heterogeneous and feature significant methodological weaknesses. Overall, data currently available mostly correlate higher levels of alexithymia with a less favorable outcome in ED. Accordingly, alexithymia is seen as a relevant treatment target with the aim of achieving recovery of these patients. Treatments focusing on improving alexithymic traits, and specifically those targeting emotions, seem to show greater efficacy, although alexithymia levels often remain high even after specific treatment. Further investigations are needed to overcome the methodological limitations of previous studies, to understand the actual impact of alexithymia on ED outcome, and to allow more precise implications for treatment to be drawn. Additional research should also be undertaken to specify which of the alexithymic dimensions are specifically relevant to the course and outcome of ED, and to identify treatment protocols producing a significantly greater efficacy in ED patients with relevant alexithymic traits.
很大比例的饮食失调(ED)患者在治疗后未能完全康复。为了改善治疗效果,识别预后预测因素并根据新的治疗目标建立个性化护理方法至关重要,这有助于患者获得循证治疗。在被提出作为ED预后预测因素的心理因素中,述情障碍备受关注。本文的目的是对与述情障碍相关的文献进行系统综述,特别是在其对ED治疗的影响方面。具体而言,将探讨述情障碍作为预后预测因素的作用以及在治疗选择中应考虑的因素等问题。还将考虑治疗对述情障碍的影响。使用PubMed、PsycINFO和Scopus数据库,基于以下关键词对所有以英文发表的相关文献进行了检索:述情障碍、神经性厌食症、神经性贪食症、饮食失调和治疗;未设置时间限制。尽管述情障碍具有临床相关性,但关于上述方面发表的研究数量有限,且这些研究在很大程度上具有异质性,存在显著的方法学弱点。总体而言,目前可得的数据大多表明述情障碍水平较高与ED患者预后较差相关。因此,述情障碍被视为实现这些患者康复的一个相关治疗目标。专注于改善述情障碍特质,特别是针对情绪的治疗,似乎显示出更大的疗效,尽管即使经过特定治疗,述情障碍水平往往仍居高不下。需要进一步研究以克服先前研究的方法学局限性,了解述情障碍对ED预后的实际影响,并得出更精确的治疗意义。还应开展更多研究,以明确述情障碍的哪些维度与ED的病程和预后特别相关,并确定对具有相关述情障碍特质的ED患者产生显著更大疗效的治疗方案。