Yang Xiao-Fei, Hu Xu-Hong, Feng Chao, Loh Teck-Peng
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.
Chem Commun (Camb). 2015 Feb 14;51(13):2532-5. doi: 10.1039/c4cc09330e.
A Rh(III)-catalyzed regioselective C-H alkenylation and alkynylation of indolines is described. This protocol relies on the use of a removable pyridinyl directing group to access valuable C-7 functionalized indoline scaffolds with ample substrate scope and broad functional group tolerance.
本文描述了一种铑(III)催化的吲哚啉区域选择性C-H烯基化和炔基化反应。该方法依赖于使用一个可去除的吡啶基导向基团，以获得具有广泛底物范围和良好官能团耐受性的有价值的C-7官能化吲哚啉骨架。
