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米特罗维察儿童血铅水平与血红蛋白水平之间的相关性。

Correlation between blood lead level and hemoglobin level in mitrovica children.

作者信息

Kutllovci-Zogaj Drita, Krasniqi Selvete, Elezaj Isa, Ramadani Naser, Gjergji Tahire, Zogaj Dukagjin, Kutllovci Arben, Jaka Arbëresha, Ukëhaxhaj Antigona, Gashi Sanije, Bince Ergyl

机构信息

Faculty of medicine, University of Prishtina, Prishtina, Kosova ; Faculty of medicine, University of Prishtina, Prishtina, Kosova.

University Clinical Center of Kosova, Prishtina, Kosova.

出版信息

Med Arch. 2014 Oct;68(5):324-8. doi: 10.5455/medarh.2014.68.324-328. Epub 2014 Oct 15.

Abstract

INTRODUCTION

Lead toxicity is a serious health threat, especially in developing countries due to environmental pollution. It was thus aimed to investigate correlation between blood lead level and concentration level of hemoglobin in the blood of children involved in research.

MATERIAL AND METHODS

The research included 250 children of which 31(12.4%) kindergarten children, 166 (66.4%) of primary school pupils in Mitrovica and 53(21.2%) of primary school pupils in Shtime as control group. From the 250 children included in the survey 129 or 51.6% were female children and 48.4% male children. Children were selected randomly, while tests for concentration of Pb and blood hemoglobin were done at the National Institute of Public Health.

RESULTS

The average value of blood lead level of Mitrovica pupils was 2.4 µg/dL (SD±1.9µg/dL), range 0.5 to 16.3µg/dL. The average value of blood lead level of Shtime pupils was 2.3µg/dL (SD±0.7µg/dL), range 1.2 to 5.2 µg/dL with no statistical difference (P = 0.191). The average value of blood lead level in kindergarten children of Mitrovica was 3.8µg/dL (SD±1.3µg/dL), range 2.2 to 7.7µg/dL with significant difference between the average values of blood lead levels of pupils and kindergarten children of Mitrovica (P <0.0001). The average value of hemoglobin in the pupils of Mitrovica was 14.0g/dL(SD± 3.7g/dL), range 9.4 to 25.6 g/dL. The average value of hemoglobin to pupils of Shtime was 11.4g/dl(SD±0.8 g/dl), range 9.2 to 13.0 g/dl with significant difference between mean values of hemoglobin pupils of Mitrovica and Shtime (U '= 6440.0, P <0.0001). With Spearman correlation is found significant correlation of a medium scale (r = -0.305, df = 248, p <0.0001) between blood lead levels and hemoglobin level in the blood.

摘要

引言

铅中毒是一种严重的健康威胁,尤其是在发展中国家,因为环境污染。因此,本研究旨在调查参与研究的儿童血铅水平与血液中血红蛋白浓度水平之间的相关性。

材料与方法

该研究纳入了250名儿童,其中31名(12.4%)是米特罗维察的幼儿园儿童,166名(66.4%)是米特罗维察的小学生,53名(21.2%)是什蒂姆的小学生作为对照组。在参与调查的250名儿童中,129名(51.6%)为女童,48.4%为男童。儿童是随机选取的,而铅浓度和血血红蛋白检测在国家公共卫生研究所进行。

结果

米特罗维察小学生的血铅水平平均值为2.4µg/dL(标准差±1.9µg/dL),范围为0.5至16.3µg/dL。什蒂姆小学生的血铅水平平均值为2.3µg/dL(标准差±0.7µg/dL),范围为1.2至5.2µg/dL,无统计学差异(P = 0.191)。米特罗维察幼儿园儿童的血铅水平平均值为3.8µg/dL(标准差±1.3µg/dL),范围为2.2至7.7µg/dL,米特罗维察小学生和幼儿园儿童的血铅水平平均值之间存在显著差异(P <0.0001)。米特罗维察小学生的血红蛋白平均值为14.0g/dL(标准差±3.7g/dL),范围为9.4至25.6g/dL。什蒂姆小学生的血红蛋白平均值为11.4g/dl(标准差±0.8g/dl),范围为9.2至13.0g/dl,米特罗维察和什蒂姆小学生血红蛋白平均值之间存在显著差异(U'= 644,0.0,P <0.0001)。通过Spearman相关性分析发现,血铅水平与血液中血红蛋白水平之间存在中等程度的显著相关性(r = -0.305,自由度= 248,p <0.0001)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2be/4269539/86bae4a32c7e/MA-68-324-g006.jpg

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