Chattopadhyay B P, Gangopadhyay P K, Das Anirban, Alam Sk Jane, Hossain Mubarak, Chowdhury Anirban, Kundu Amar
Regional Occupational Health Centre (Eastern), (Indian Council of Medical Research), Block DP, Sector-V, Salt Lake City, Kolkata, India.
Indian J Occup Environ Med. 2014 May;18(2):57-63. doi: 10.4103/0019-5278.146891.
The tobacco dusts get air borne during biddi making and it is inhaled by the biddi binders, which affects their health.
In a follow-up study, 86 biddi binders (male, 41; female, 45) were studied at a gap of 2 years. A high respiratory morbidity was observed among males than females both in the initial and follow-up study. The main complaints such as cough, sputum, and breathlessness showed high prevalence rates in the follow-up study. The high prevalence rates of weakness, giddiness, chronic diarrhea, and dyspepsia were noted in most of the cases the above complaints showed higher rates in the follow-up study. Pulmonary function test (PFT) values in the follow-up study of male and female biddi binders showed lowered compared with the initial study of same gender. In male and female biddi binders, the lung volumes SVC, FVC, FEV1, and the flow rates FEF0.2-1.2 l, FEF25%-75%, FEF75%-85% were significantly lowered in the follow-up study compared with the initial study. Age-related decrement in PFT was observed in both the studies. In nonsmokers, smokers, and ex-smokers, the PFT values are lowered. The current smokers have the lowest values in both the studies. With the administration of the bronchodilator aerosol (salbutamol) in 63 biddi binders (male, 27; female, 36), the effect of bronchodilator aerosol on the PFT parameters showed significant changes as all PFT parameters showed positive bronchodilatation.
The pattern of bronchodilator response on PFT values of the biddi binders suggests that the obstructions in the airways are reversible in nature.
在制作比迪烟的过程中,烟草粉尘会飘浮在空气中,比迪烟装订工人会吸入这些粉尘,这会影响他们的健康。
在一项随访研究中,对86名比迪烟装订工人(男性41名,女性45名)进行了为期2年的研究。在初始研究和随访研究中,男性的呼吸道发病率均高于女性。咳嗽、咳痰和呼吸困难等主要症状在随访研究中的患病率较高。大多数病例中,虚弱、头晕、慢性腹泻和消化不良的患病率较高,上述症状在随访研究中的发病率更高。与同性别初始研究相比,男性和女性比迪烟装订工人随访研究中的肺功能测试(PFT)值降低。在男性和女性比迪烟装订工人中,随访研究与初始研究相比肺容量SVC、FVC、FEV1以及流速FEF0.2 - 1.2升、FEF25% - 75%、FEF75% - 85%均显著降低。两项研究均观察到与年龄相关的PFT下降。在不吸烟者、吸烟者和已戒烟者中,PFT值均降低。在两项研究中,当前吸烟者的PFT值最低。对63名比迪烟装订工人(男性27名,女性36名)使用支气管扩张气雾剂(沙丁胺醇)后,支气管扩张气雾剂对PFT参数的影响显示出显著变化,因为所有PFT参数均显示出正性支气管扩张作用。
支气管扩张剂对比迪烟装订工人PFT值的反应模式表明气道阻塞本质上是可逆的。