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科索沃成年男性体重及体重指数与骨密度的关系。

Relationship of weight and body mass index with bone mineral density in adult men from kosovo.

作者信息

Hoxha Rexhep, Islami Hilmi, Qorraj-Bytyqi Hasime, Thaçi Shpetim, Bahtiri Elton

机构信息

Department of Pharmacology, Faculty of Medicine, University of Prishtina, Kosovo.

Department of Physiology and Immunology, Faculty of Medicine, University of Prishtina, Kosovo.

出版信息

Mater Sociomed. 2014 Oct;26(5):306-8. doi: 10.5455/msm.2014.26.306-308. Epub 2014 Oct 29.

Abstract

BACKGROUND AND OBJECTIVE

Body weight and body mass index (BMI) are considered strong predictors of osteoporotic fractures, though optimal BMI levels remain unsettled. There are several studies conducted on women about the relationship between BMI and bone mineral density (BMD), and just a few so far on men. Therefore, the objective of current study was to analyze the relationship between weight and BMI and BMD measured in lumbar spine (L1-L4), femur neck and total hip in 64 men from Kosovo.

METHODS

This cross-sectional study included a population of 64 men divided into three BMI groups. Dual-energy X-ray absorptiometry (DEXA) measurements were done in all the study participants.

RESULTS

Pearson's correlation analysis showed a significant positive correlation between weight and BMI and BMD in femur neck and in total hip, and a significant negative correlation between age and femur neck BMD. Age-adjusted linear regression analysis showed that weight and BMI had a significant positive association with BMD levels.

CONCLUSION

Although the results show significant relationship between BMI and BMD, the negative relationship between age and femur neck BMD may serve as guidance to initiate early assessment of the BMD in this region as well as preventive measures of osteoporosis and fractures among ageing men population.

摘要

背景与目的

体重和体重指数(BMI)被认为是骨质疏松性骨折的有力预测指标,尽管最佳BMI水平仍未确定。关于女性BMI与骨密度(BMD)之间的关系已有多项研究,但迄今为止针对男性的研究较少。因此,本研究的目的是分析来自科索沃的64名男性的体重、BMI与腰椎(L1-L4)、股骨颈和全髋部测量的骨密度之间的关系。

方法

这项横断面研究纳入了64名男性,分为三个BMI组。对所有研究参与者进行了双能X线吸收法(DEXA)测量。

结果

Pearson相关分析显示,体重与BMI以及股骨颈和全髋部的骨密度之间存在显著正相关,年龄与股骨颈骨密度之间存在显著负相关。年龄调整线性回归分析表明,体重和BMI与骨密度水平存在显著正相关。

结论

尽管结果显示BMI与骨密度之间存在显著关系,但年龄与股骨颈骨密度之间的负相关关系可为在该区域启动骨密度早期评估以及老年男性人群骨质疏松症和骨折的预防措施提供指导。

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本文引用的文献

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Male osteoporosis.男性骨质疏松症
Reumatismo. 2014 Jul 28;66(2):136-43. doi: 10.4081/reumatismo.2014.786.
2
Obesity and fracture risk.肥胖与骨折风险。
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