Rexhepi Sylejman, Bahtiri Elton, Rexhepi Mjellma, Sahatciu-Meka Vjollca, Rexhepi Blerta
Clinic of Rheumatology, University Clinical Center of Kosovo, Prishtina, Kosovo.
Clinic of Endocrinology, University Clinical Center of Kosovo, Prishtina, Kosovo.
Mater Sociomed. 2015 Aug;27(4):259-62. doi: 10.5455/msm.2015.27.259-262.
Body weight and body mass index (BMI) are considered potentially modifiable determinants of bone mass. Therefore, the aim of this study was to explore the association between body weight and body mass index (BMI) with total hip and lumbar spine bone mineral density (BMD).
This cross-sectional study included a population of 100 women and 32 men from Kosovo into three BMI groups. All the study subjects underwent dual-energy X-ray absorptiometry (DXA) measurements.
Total hip BMD levels of obese menopausal and premenopausal women and men were significantly higher compared to overweight or normal weight subjects, while lumbar spine BMD levels of only menopausal women and men were higher among obese subjects. Age-adjusted linear regression analysis showed that BMI is a significant independent associate of lumbar spine and total hip BMD in menopausal women and men.
Despite positive association between BMI and lumbar spine and total hip BMD in menopausal women, presence of more obese and osteoporotic subjects among menopausal women represent a population at risk for fractures because of poor balance and frequent falls; therefore, both obesity and osteoporosis prevention efforts should begin early on in life.
体重和体重指数(BMI)被认为是骨量潜在的可改变决定因素。因此,本研究的目的是探讨体重和体重指数(BMI)与全髋部和腰椎骨密度(BMD)之间的关联。
这项横断面研究纳入了来自科索沃的100名女性和32名男性,分为三个BMI组。所有研究对象均接受了双能X线吸收法(DXA)测量。
肥胖的绝经后和绝经前女性及男性的全髋部BMD水平显著高于超重或正常体重的受试者,而仅绝经后女性和男性的腰椎BMD水平在肥胖受试者中较高。年龄调整线性回归分析表明,BMI是绝经后女性和男性腰椎和全髋部BMD的显著独立相关因素。
尽管绝经后女性的BMI与腰椎和全髋部BMD之间存在正相关,但绝经后女性中肥胖和骨质疏松症患者较多,由于平衡能力差和频繁跌倒,她们属于骨折高危人群;因此,肥胖和骨质疏松症的预防工作都应在生命早期开始。