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3
The Pathophysiology of Primary Hip Osteoarthritis may Originate from Bone Alterations.原发性髋关节骨关节炎的病理生理学可能源于骨质改变。
Open Rheumatol J. 2013 Nov 29;7:112-8. doi: 10.2174/1874312920130930003. eCollection 2013.
4
Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes.骨关节炎中的软骨下骨:对危险因素和微观结构变化的洞察
Arthritis Res Ther. 2013;15(6):223. doi: 10.1186/ar4405.
5
Joint pain undergoes a transition in accordance with signal changes of bones detected by MRI in hip osteoarthritis.在髋关节骨关节炎中,关节疼痛会根据MRI检测到的骨骼信号变化而发生转变。
Open Rheumatol J. 2013 Sep 30;7:67-74. doi: 10.2174/1874312920130823002. eCollection 2013.
6
Subchondral bone marrow lesions associated with knee osteoarthritis.与膝关节骨关节炎相关的软骨下骨髓损伤
Am J Orthop (Belle Mead NJ). 2012 Sep;41(9):413-7.
7
Osteoarthritis: histology and pathogenesis.骨关节炎:组织学与发病机制
Wien Med Wochenschr. 2013 May;163(9-10):212-9. doi: 10.1007/s10354-012-0168-y. Epub 2012 Dec 20.
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Subchondral insufficiency fractures of the femoral head.股骨头软骨下不全骨折。
Clin Orthop Surg. 2012 Sep;4(3):173-80. doi: 10.4055/cios.2012.4.3.173. Epub 2012 Aug 14.
9
Bone remodelling in osteoarthritis.骨关节炎中的骨重建。
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Metabolic factors in osteoarthritis: obese people do not walk on their hands.骨关节炎中的代谢因素:肥胖者不会用手行走。
Arthritis Res Ther. 2012 Jul 19;14(4):123. doi: 10.1186/ar3894.

膝关节骨关节炎患者的快速骨质破坏。病例报告及文献综述。

Rapid bone destruction in a patient with knee osteoarthritis. A case report and review of the literature.

作者信息

Komatsu Masatoshi, Kamimura Mikio, Nakamura Yukio, Mukaiyama Keijiro, Ikegami Shota, Uchiyama Shigeharu, Kato Hiroyuki

机构信息

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Center of Osteoporosis and Spinal Disorders, Kamimura Orthopaedic Clinic, Matsumoto, Japan.

出版信息

Clin Cases Miner Bone Metab. 2014 Sep;11(3):232-5.

PMID:25568659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4269149/
Abstract

We report the clinical outcome of an elderly man with knee osteoarthritis (OA) accompanied with recurring severe joint pain. He had no history of trauma to the affected knee. Plain radiographs and magnetic resonance imaging uncovered rapid and severe bone deformity, which likely led to the patient's progressed radiographic OA. These findings indicate that a pathophysiology of OA may be bone alterations.

摘要

我们报告了一名患有膝关节骨关节炎(OA)并伴有反复严重关节疼痛的老年男性的临床结果。他患侧膝关节无外伤史。X线平片和磁共振成像发现了快速且严重的骨骼畸形,这可能导致了患者影像学上OA的进展。这些发现表明,OA的病理生理学可能是骨骼改变。