Kamimura Mikio, Nakamura Yukio, Ikegami Shota, Uchiyama Shigeharu, Kato Hiroyuki
Center of Osteoporosis and Spinal Disorders: Kamimura Orthopaedic Clinic, Matsumoto 399-0021, Japan.
Open Rheumatol J. 2013 Sep 30;7:67-74. doi: 10.2174/1874312920130823002. eCollection 2013.
In this study, we aimed to investigate whether joint pain is derived from cartilage or bone alterations.
We reviewed 23 hip joints of 21 patients with primary hip osteoarthritis (OA), which were classified into Kellgren-Laurence (KL) grading I to IV. Plain radiographs and magnetic resonance imaging (MRI) were obtained from all of the 23 joints. Two of the 21 patients had bilateral hip OA. Pain was assessed based on the pain scale of Denis. A Welch t test was performed for age, height, weight, body mass index, bone mineral density, and a Mann-Whitney U test was performed for KL grading.
Four of 8 hip joints with pain and OA showed broad signal changes detected by MRI. Fourteen hip joints without pain, but with OA did not show broad signal changes by MRI. Collectively, MRI analyses showed that broad signal changes in OA cases without joint pain or with a slight degree of joint pain were not observed, while broad signal changes were observed in OA cases with deteriorated joint pain.
Our findings suggest that hip joint pain might be associated with bone signal alterations in the hips of OA patients.
在本研究中，我们旨在调查关节疼痛是否源自软骨或骨骼改变。
我们回顾了21例原发性髋骨关节炎（OA）患者的23个髋关节，这些髋关节被分类为凯尔格伦-劳伦斯（KL）分级I至IV级。对所有23个关节进行了X线平片和磁共振成像（MRI）检查。21例患者中有2例为双侧髋OA。根据丹尼斯疼痛量表评估疼痛情况。对年龄、身高、体重、体重指数、骨密度进行了韦尔奇t检验，对KL分级进行了曼-惠特尼U检验。
8个有疼痛和OA的髋关节中有4个显示MRI检测到广泛的信号改变。14个无疼痛但有OA的髋关节未显示MRI检测到广泛的信号改变。总体而言，MRI分析表明，在无关节疼痛或有轻度关节疼痛的OA病例中未观察到广泛的信号改变，而在关节疼痛恶化的OA病例中观察到广泛的信号改变。
我们的研究结果表明，髋关节疼痛可能与OA患者髋部的骨信号改变有关。
