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如何为哮喘或反复喘息的个体儿童匹配最佳的现有吸入装置。

How to match the optimal currently available inhaler device to an individual child with asthma or recurrent wheeze.

机构信息

Department of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital AMC, Amsterdam, The Netherlands.

Area de Pediatria, Pabellon Docente Universitario Ctra., Murcia, Spain.

出版信息

NPJ Prim Care Respir Med. 2015 Jan 8;25:14088. doi: 10.1038/npjpcrm.2014.88.

DOI:10.1038/npjpcrm.2014.88
PMID:25568979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4532150/
Abstract

Inhaled medications are the cornerstone of treatment in early childhood wheezing and paediatric asthma. A match between patient and device and a correct inhalation technique are crucial for good asthma control. The aim of this paper is to propose an inhaler strategy that will facilitate an inhaler choice most likely to benefit different groups of children. The main focus will be on pressurised metered dose inhalers and dry powder inhalers. In this paper we will discuss (1) practical difficulties with the devices and with inhaled therapy and (2) the optimal location for deposition of medicines in the lungs, and (3) we will propose a practical and easy way to make the best match between the inhaler device and the individual patient. We hope that this paper will contribute to an increased likelihood of treatment success and improved adherence to therapy.

摘要

吸入药物是儿童期喘息和儿童哮喘治疗的基石。患者与设备的匹配和正确的吸入技术对于良好的哮喘控制至关重要。本文旨在提出一种吸入器策略,以方便选择最有可能使不同儿童群体受益的吸入器。主要重点将放在压力定量吸入器和干粉吸入器上。在本文中,我们将讨论(1)设备和吸入治疗的实际困难,以及(2)药物在肺部的最佳沉积位置,(3)我们将提出一种实用且简单的方法,使吸入器设备与个体患者之间达到最佳匹配。我们希望本文能提高治疗成功率和提高治疗依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f801/4532150/7643c8c44575/npjpcrm201488-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f801/4532150/7643c8c44575/npjpcrm201488-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f801/4532150/7643c8c44575/npjpcrm201488-f1.jpg

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J Asthma. 2013 Jun;50(5):505-13. doi: 10.3109/02770903.2013.783064. Epub 2013 Apr 15.
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