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On the role of the endogenous opioid system in regulating epidermal homeostasis.
J Invest Dermatol. 2015 Feb;135(2):333-334. doi: 10.1038/jid.2014.458.
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The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3.
J Invest Dermatol. 2015 Feb;135(2):471-480. doi: 10.1038/jid.2014.370. Epub 2014 Sep 1.
3
Opioid receptor delta as a global modulator of skin differentiation and barrier function repair.
Int J Cosmet Sci. 2015 Aug;37(4):386-94. doi: 10.1111/ics.12207. Epub 2015 Mar 9.
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Role of PKC-delta as a signal mediator in epidermal barrier homeostasis.
Arch Dermatol Res. 2007 May;299(2):53-7. doi: 10.1007/s00403-007-0738-9. Epub 2007 Feb 14.
5
Regulation of epidermal homeostasis through P2Y2 receptors.
Br J Pharmacol. 1999 Aug;127(7):1680-6. doi: 10.1038/sj.bjp.0702653.
7
Regulation of epidermal homeostasis and repair by phosphoinositide 3-kinase.
J Cell Sci. 2006 Oct 1;119(Pt 19):4033-46. doi: 10.1242/jcs.03175. Epub 2006 Sep 12.
9
Diffusible factors released by fibroblasts support epidermal morphogenesis and deposition of basement membrane components.
Wound Repair Regen. 2004 May-Jun;12(3):359-67. doi: 10.1111/j.1067-1927.2004.012306.x.
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Extracellular signal-regulated kinase/mitogen-activated protein kinases block internalization of delta-opioid receptors.
J Pharmacol Exp Ther. 2004 May;309(2):776-85. doi: 10.1124/jpet.103.061788. Epub 2004 Jan 23.

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1
Neuroendocrine signaling in the skin with a special focus on the epidermal neuropeptides.
Am J Physiol Cell Physiol. 2022 Dec 1;323(6):C1757-C1776. doi: 10.1152/ajpcell.00147.2022. Epub 2022 Nov 1.
2
Sex disparity in skin carcinogenesis and potential influence of sex hormones.
Skin Health Dis. 2021 Apr 1;1(2):e27. doi: 10.1002/ski2.27. eCollection 2021 Jun.
3
Opioidergic Signaling-A Neglected, Yet Potentially Important Player in Atopic Dermatitis.
Int J Mol Sci. 2022 Apr 8;23(8):4140. doi: 10.3390/ijms23084140.
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Pruritus: A Sensory Symptom Generated in Cutaneous Immuno-Neuronal Crosstalk.
Front Pharmacol. 2022 Mar 7;13:745658. doi: 10.3389/fphar.2022.745658. eCollection 2022.
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Environmental Stressors on Skin Aging. Mechanistic Insights.
Front Pharmacol. 2019 Jul 9;10:759. doi: 10.3389/fphar.2019.00759. eCollection 2019.
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Investigating endogenous µ-opioid receptors in human keratinocytes as pharmacological targets using novel fluorescent ligand.
PLoS One. 2017 Dec 6;12(12):e0188607. doi: 10.1371/journal.pone.0188607. eCollection 2017.
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Molecular Pharmacology of δ-Opioid Receptors.
Pharmacol Rev. 2016 Jul;68(3):631-700. doi: 10.1124/pr.114.008979.
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On the role of skin in the regulation of local and systemic steroidogenic activities.
Steroids. 2015 Nov;103:72-88. doi: 10.1016/j.steroids.2015.04.006. Epub 2015 May 16.

本文引用的文献

1
The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3.
J Invest Dermatol. 2015 Feb;135(2):471-480. doi: 10.1038/jid.2014.370. Epub 2014 Sep 1.
2
Role of lipids in the formation and maintenance of the cutaneous permeability barrier.
Biochim Biophys Acta. 2014 Mar;1841(3):280-94. doi: 10.1016/j.bbalip.2013.11.007. Epub 2013 Nov 18.
3
Key role of CRF in the skin stress response system.
Endocr Rev. 2013 Dec;34(6):827-84. doi: 10.1210/er.2012-1092. Epub 2013 Aug 12.
4
Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system.
Adv Anat Embryol Cell Biol. 2012;212:v, vii, 1-115. doi: 10.1007/978-3-642-19683-6_1.
6
Regulated proenkephalin expression in human skin and cultured skin cells.
J Invest Dermatol. 2011 Mar;131(3):613-22. doi: 10.1038/jid.2010.376. Epub 2010 Dec 30.
7
A nervous breakdown in the skin: stress and the epidermal barrier.
J Clin Invest. 2007 Nov;117(11):3166-9. doi: 10.1172/JCI33508.
8
Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology.
J Invest Dermatol. 2006 Sep;126(9):1966-75. doi: 10.1038/sj.jid.5700421.
9
Innate immunity: involvement of new neuropeptides.
Trends Microbiol. 2003 Dec;11(12):585-92. doi: 10.1016/j.tim.2003.10.001.
10
Neuroendocrinology of the skin.
Endocr Rev. 2000 Oct;21(5):457-87. doi: 10.1210/edrv.21.5.0410.

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