Rodea-Montero Edel Rafael, Evia-Viscarra María Lola, Apolinar-Jiménez Evelia
Department of Research, Hospital Regional de Alta Especialidad del Bajío, Boulevard Milenio 130, San Carlos la Roncha, 37660 León, GTO, Mexico.
Department of Pediatric Endocrinology, Hospital Regional de Alta Especialidad del Bajío, Boulevard Milenio 130, San Carlos la Roncha, 37660 León, GTO, Mexico.
Int J Endocrinol. 2014;2014:195407. doi: 10.1155/2014/195407. Epub 2014 Dec 9.
Objective. To identify the degree of association between anthropometric indices and components of metabolic syndrome (MS) and to determine optimal cut-off points of these indices for predicting MS in obese adolescents. Methods. A cross-sectional study with a sample of (n = 110) Mexican obese adolescents grouped by sex and the presence/absence of MS. BMI percentile, waist circumference (WC), and waist-to-height ratio (WHtR) were tested. ROC curves of the anthropometric indices were created to identify whether an index was a significant predictor of MS. Results. BMI percentile, WC, and WHtR were significantly correlated with systolic and diastolic blood pressure. As predictors of MS overall patients, the BMI percentile generated an area under curve (AUC) of 0.651 (P = 0.008), cut-off point above the 99th percentile. WC generated an AUC of 0.704 (P < 0.001), cut-off point of ≥90 cm. WHtR demonstrated an AUC of 0.652 (P = 0.008), cut-off point of 0.60. WHtR ≥0.62 and WHtR ≥0.61 generate AUC of 0.737 (P = 0.006) and AUC of 0.717 (P = 0.014) for predicting hypertension and insulin resistance, respectively, in females. Conclusion. WHtR is a better tool than WC and BMI for identifying cardiometabolic risk. The overall criterion (WHtR ≥ 0.6) could be appropriate for predicting MS in obese Mexican adolescents.
目的。确定人体测量指标与代谢综合征(MS)各组分之间的关联程度,并确定这些指标用于预测肥胖青少年患MS的最佳切点。方法。一项横断面研究,样本为110名墨西哥肥胖青少年,按性别以及是否患有MS进行分组。对体重指数百分位数、腰围(WC)和腰高比(WHtR)进行检测。绘制人体测量指标的ROC曲线,以确定某一指标是否为MS的显著预测因子。结果。体重指数百分位数、WC和WHtR与收缩压和舒张压显著相关。作为MS总体患者的预测因子,体重指数百分位数的曲线下面积(AUC)为0.651(P = 0.008),切点在第99百分位数以上。WC的AUC为0.704(P < 0.001),切点≥90 cm。WHtR的AUC为0.652(P = 0.008),切点为0.60。对于预测女性高血压和胰岛素抵抗,WHtR≥0.62和WHtR≥0.61的AUC分别为0.737(P = 0.006)和0.717(P = 0.014)。结论。对于识别心脏代谢风险,WHtR是比WC和体重指数更好的工具。总体标准(WHtR≥0.6)可能适用于预测肥胖墨西哥青少年患MS的情况。