Sabatini C, Wu Z
Oper Dent. 2015 Sep-Oct;40(5):548-57. doi: 10.2341/14-190-L. Epub 2015 Jan 9.
Desensitizing agents are used, almost as routine practice, in many adhesive restorative procedures. There is still debate as to their effect in dentin bonding, particularly with self-etching adhesives. The present study aimed to evaluate the effect of different desensitizing agents on the bond strength of mild and strong self-etching adhesive systems to dentin.
One hundred twenty recently extracted, noncarious human molars were used to obtain superficial dentin substrate for bonding. No desensitizer was used in the control groups. The experimental groups were pretreated with Gluma Desensitizer, MicroPrime B, and Dentin Desensitizer immediately prior to bonding with self-etching adhesives Optibond XTR, Xeno IV, and iBond. A bonding jig was used to fabricate composite cylinders, which were stored for either 24 hours or three months, after which the shear bond strength (SBS) was evaluated using a notched-edge testing device at a crosshead speed of 1 mm/min. Failure mode distribution was also evaluated at 24 hours and three months. A two-way analysis of variance, Tukey test, and Student t-test, with a significance level of p<0.05, were used for data analysis.
At 24 hours, there was no significant difference in SBS when the same adhesive was used with any of the experimental desensitizing agents compared with the control group without desensitizer. However, at three months, Dentin Desensitizer bonded with Optibond XTR demonstrated significantly lower SBS (p<0.001), while Gluma bonded with iBond showed significantly higher SBS values (p=0.034) relative to their corresponding control group. Only MicroPrime B bonded with Xeno IV and iBond with no desensitizer demonstrated a significant reduction in SBS after three months (p=0.034 and p=0.002, respectively). The most prevalent type of failure was adhesive.
Desensitizing agents can be used in combination with self-etching adhesives to control hypersensitivity without adversely affecting their bond strength to dentin.
在许多粘结修复操作中,脱敏剂几乎作为常规手段使用。关于它们在牙本质粘结中的效果,尤其是与自酸蚀粘结剂的效果,仍存在争议。本研究旨在评估不同脱敏剂对轻度和重度自酸蚀粘结系统与牙本质粘结强度的影响。
使用120颗近期拔除的无龋人类磨牙获取用于粘结的表层牙本质基质。对照组不使用脱敏剂。实验组在使用自酸蚀粘结剂Optibond XTR、Xeno IV和iBond粘结之前,立即用Gluma脱敏剂、MicroPrime B和牙本质脱敏剂进行预处理。使用粘结夹具制作复合圆柱体,将其储存24小时或3个月,之后使用缺口边缘测试装置以1毫米/分钟的十字头速度评估剪切粘结强度(SBS)。在24小时和3个月时也评估了失效模式分布。采用显著性水平为p<0.05的双向方差分析、Tukey检验和Student t检验进行数据分析。
在24小时时,与未使用脱敏剂的对照组相比,使用相同粘结剂并搭配任何一种实验性脱敏剂时,SBS没有显著差异。然而,在3个月时,与Optibond XTR粘结的牙本质脱敏剂显示出显著更低的SBS(p<0.001),而与iBond粘结的Gluma显示出相对于相应对照组显著更高的SBS值(p=0.034)。只有与Xeno IV粘结的MicroPrime B以及未使用脱敏剂与iBond粘结的情况在3个月后显示出SBS显著降低(分别为p=0.034和p=0.002)。最常见的失效类型是粘结性失效。
脱敏剂可与自酸蚀粘结剂联合使用以控制过敏,而不会对其与牙本质的粘结强度产生不利影响。