Davalloo Reza, Tavangar Seyedeh Maryam, Ebrahimi Heshmatollah, Darabi Farideh, Mahmoudi Shima
Dental Sciences Research Center, Dept. of Restorative Dentistry, Faculty of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
Dept. of Medicinal Chemistry, School of Pharmacy, Guilan University of Medical Sciences, Rasht, Iran.
J Dent (Shiraz). 2020 Jun;21(2):111-118. doi: 10.30476/DENTJODS.2019.77756.0.
Etching process on dentin can activate matrix metalloproteinase (MMP) which hydrolyze organic matrix of demineralized dentin. Gluma and chlorhexidine could inhibit the activation of MMP.
The aim of the study was to evaluate the effect of a new desensitizing material consisting of Gluma and chlorhexidine together on the shear bond strength and bond durability of composite restorations.
One hundred and twenty caries-free extracted premolars were sectioned horizontally from one third of the coronal crown to expose flat dentin surface and randomly divided into 4 groups. In the control group, no surface treatment was used. In the first group chlorhexidine (CHX) 2%, in the second group, new material (NM) and in third group Gluma desensitizer (GD) was applied after etching and before bonding(total-etch bonding system). After the bonding process, the composite was placed on the surface of the samples using a cylindrical mold. Then, the shear bond strengths of half of the specimens were measured after 24 hours and the other half after 6 months of storage in distilled water and thermocycling. The failure types of specimens were evaluated with a stereomicroscope. Data were analyzed using One-way Anova and Tukey's Post Hoc tests in SPSS software.
After 6 months, the bond strength decreased in all groups and differences were statistically significant (= 0.002).The highest shear bond strength was observed after 6 months in the NM group and the GD group with no statistically significant difference. The 24-hour bond strengths were not significant between groups. Mix failure had the highest rate in all groups.
It can be concluded that the effect of combination of chlorhexidine and Gluma on maintaining the integrity and strength of bond over time is similar to Gluma compound alone and they have better effect than chlorhexidine.
牙本质酸蚀过程可激活基质金属蛋白酶(MMP),该酶能水解脱矿牙本质的有机基质。Gluma和氯己定可抑制MMP的激活。
本研究旨在评估一种由Gluma和氯己定组成的新型脱敏材料对复合树脂修复体剪切粘结强度和粘结耐久性的影响。
将120颗无龋的离体前磨牙从牙冠三分之一处水平切开,暴露出平坦的牙本质表面,并随机分为4组。对照组不进行表面处理。第一组使用2%氯己定(CHX),第二组使用新型材料(NM),第三组在酸蚀后、粘结前使用Gluma脱敏剂(GD)(全酸蚀粘结系统)。粘结完成后,使用圆柱形模具将复合树脂置于样本表面。然后,一半样本在24小时后测量剪切粘结强度,另一半在蒸馏水中储存6个月并经过热循环后测量。用体视显微镜评估样本的失败类型。数据在SPSS软件中使用单因素方差分析和Tukey事后检验进行分析。
6个月后,所有组的粘结强度均下降,差异具有统计学意义(P = 0.002)。6个月后,NM组和GD组的剪切粘结强度最高,差异无统计学意义。各组24小时的粘结强度无显著差异。混合失败在所有组中的发生率最高。
可以得出结论,氯己定和Gluma联合使用在长期维持粘结完整性和强度方面的效果与单独使用Gluma化合物相似,且比氯己定效果更好。