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经皮冠状动脉介入治疗后冠心病患者焦虑/抑郁状况的研究

Study of Anxiety/Depression in Patients with Coronary Heart Disease After Percutaneous Coronary Intervention.

作者信息

Zhang PeiYing

机构信息

Xuzhou Center Hospital, No.199 JieFang south Road, Xuzhou, 221009, Jiangsu, China.

出版信息

Cell Biochem Biophys. 2015 Jun;72(2):503-7. doi: 10.1007/s12013-014-0495-2.

DOI:10.1007/s12013-014-0495-2
PMID:25575895
Abstract

The objective of this study is to study the involvement of anxiety/depression in patients with coronary heart disease after percutaneous coronary intervention. Inpatients in the Department of Cardiology of Xuzhou Center Hospital from December 2012 to July 2014 were divided into stent group (100 cases) and the non-stent group (50 cases). Fifty cases in the stent group were treated with psychological methods, called intervention group, and other 50 cases were untreated and called non-intervention group. All patients were assessed for anxiety and depression using self-rating anxiety scale and self-rating depression scale, 1 day after admission, 1 day after coronary angiography, and when they were discharged. No significant differences were observed on biochemical criterion, and anxiety scores or depression scores between the stent and the non-stent groups before percutaneous coronary intervention (P value >0.05 for all). After percutaneous coronary intervention, anxiety/depression scores in the intervention group and non-intervention group were significantly higher than those in the non-stent group (P < 0.05). There were no significant differences between the intervention group and the non-intervention group on anxiety/depression scores (P > 0.05). On the day of discharge, the anxiety/depression scores were the lowest in the intervention group (P < 0.05). Coronary artery intervention can increase patients' anxiety/depression, but appropriate psychological intervention can reduce the negative emotions.

摘要

本研究的目的是探讨焦虑/抑郁在经皮冠状动脉介入治疗后冠心病患者中的影响。选取2012年12月至2014年7月徐州中心医院心内科住院患者,分为支架组(100例)和非支架组(50例)。支架组中的50例患者采用心理方法治疗,称为干预组,另外50例未接受治疗,称为非干预组。所有患者在入院后1天、冠状动脉造影后1天及出院时,使用焦虑自评量表和抑郁自评量表评估焦虑和抑郁情况。在经皮冠状动脉介入治疗前,支架组和非支架组在生化指标、焦虑评分或抑郁评分方面均未观察到显著差异(所有P值>0.05)。经皮冠状动脉介入治疗后,干预组和非干预组的焦虑/抑郁评分均显著高于非支架组(P<0.05)。干预组和非干预组在焦虑/抑郁评分方面无显著差异(P>0.05)。出院当天,干预组的焦虑/抑郁评分最低(P<0.05)。冠状动脉介入治疗会增加患者的焦虑/抑郁,但适当的心理干预可以减少负面情绪。

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