Basuray Anupam, Dolansky Mary, Josephson Richard, Sattar Abdus, Grady Ellen M, Vehovec Anton, Gunstad John, Redle Joseph, Fang James, Hughes Joel W
OhioHealth Heart and Vascular Physicians, Riverside Methodist Hospital, Columbus, Ohio.
Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio.
J Card Fail. 2015 Apr;21(4):323-9. doi: 10.1016/j.cardfail.2014.12.016. Epub 2015 Jan 7.
We sought to determine the rates and predictors of dietary sodium restriction and to evaluate the reliability of 24-hour urine collection as a tool to estimate dietary sodium intake in heart failure (HF) patients.
We evaluated the 24-hour urinary sodium excretion of 305 outpatients with HF and reduced ejection fraction who were educated on following a <2 g sodium diet. The mean sodium excretion according to a single sample from each participant was 3.15 ± 1.58 g, and 23% were adherent to the <2 g recommendation. One hundred sixty-eight participants provided 2 samples with urinary creatinine excretion within normative range. Averaging both resulted in a mean sodium excretion of 3.21 ± 1.20 g and lower adherence rates to the <2-gram diet: 14% versus 23% (P = .019). Multivariate logistic regression showed only male sex and higher body mass index (BMI) to be associated with nonadherence (male: odds ratio [OR] 2.20, 95% confidence interval [CI] 1.25-3.88; 1 unit BMI: OR 1.05, 95% CI 1.01-1.10). Bland-Altman plots of urinary sodium and creatinine showed poor reproducibility between samples.
In this chronic HF population, sodium consumption probably exceeds recommended amounts, particularly in men and those with higher BMI. Urine analyses were not highly reproducible, suggesting variation in both diet and urine collection.
我们试图确定饮食中钠限制的比例和预测因素,并评估24小时尿液收集作为估计心力衰竭(HF)患者饮食中钠摄入量工具的可靠性。
我们评估了305例射血分数降低的HF门诊患者的24小时尿钠排泄情况,这些患者接受了低于2克钠饮食的教育。根据每个参与者的单个样本,平均钠排泄量为3.15±1.58克,23%的患者遵守了低于2克的建议。168名参与者提供了2份尿肌酐排泄量在正常范围内的样本。将两者平均后,平均钠排泄量为3.21±1.20克,对低于2克饮食的依从率更低:14%对23%(P = 0.019)。多因素逻辑回归显示,只有男性和较高的体重指数(BMI)与不依从相关(男性:优势比[OR]2.20,95%置信区间[CI]1.25 - 3.88;BMI每增加1个单位:OR 1.05,95%CI 1.01 - 1.10)。尿钠和肌酐的Bland - Altman图显示样本间的再现性较差。
在这个慢性HF人群中,钠摄入量可能超过推荐量,尤其是男性和BMI较高的人群。尿液分析的再现性不高,表明饮食和尿液收集均存在差异。