Patros Connor H G, Alderson R Matt, Lea Sarah E, Tarle Stephanie J, Kasper Lisa J, Hudec Kristen L
Department of Psychology, Oklahoma State University, 116 North Murray, Stillwater, OK 74078-3064, United States.
Department of Psychology, Oklahoma State University, 116 North Murray, Stillwater, OK 74078-3064, United States.
Res Dev Disabil. 2015 Mar;38:134-44. doi: 10.1016/j.ridd.2014.12.016. Epub 2015 Jan 8.
The present study examined the directional relationship between choice-impulsivity and separate indices of phonological and visuospatial working memory performance in boys (aged 8-12 years) with (n=16) and without ADHD (n=19). Results indicated that high ratings of overall ADHD, inattention, and hyperactivity were significantly associated with increased impulsivity and poorer phonological and visuospatial working memory performance. Further, results from bias-corrected bootstrapped mediation analyses revealed a significant indirect effect of visuospatial working memory performance, through choice-impulsivity, on overall ADHD, inattention, and hyperactivity/impulsivity. Collectively, the findings suggest that deficits of visuospatial working memory underlie choice-impulsivity, which in turn contributes to the ADHD phenotype. Moreover, these findings are consistent with a growing body of literature that identifies working memory as a central neurocognitive deficit of ADHD.
本研究考察了患有(n = 16)和未患有注意力缺陷多动障碍(ADHD,n = 19)的8至12岁男孩中,选择冲动性与语音和视觉空间工作记忆表现的单独指标之间的方向性关联。结果表明,ADHD总体、注意力不集中和多动的高分与冲动性增加以及较差的语音和视觉空间工作记忆表现显著相关。此外,偏差校正的自抽样中介分析结果显示,视觉空间工作记忆表现通过选择冲动性对ADHD总体、注意力不集中以及多动/冲动性产生显著的间接影响。总体而言,研究结果表明视觉空间工作记忆缺陷是选择冲动性的基础,而选择冲动性反过来又导致了ADHD表型。此外,这些发现与越来越多将工作记忆确定为ADHD核心神经认知缺陷的文献一致。