Herrera Antonio, Mateo Jesús, Gil-Albarova Jorge, Lobo-Escolar Antonio, Artigas José M, López-Prats Fernando, Mesa Manuel, Ibarz Elena, Gracia Luis
Department of Surgery, University of Zaragoza, Domingo Miral s/n, 50009 Zaragoza, Spain; Aragón Health Sciences Institute, Zaragoza, Spain.
Department of Surgery, University of Zaragoza, Domingo Miral s/n, 50009 Zaragoza, Spain; Department of Orthopaedic Surgery and Traumatology, Miguel Servet University Hospital, Avda Isabel la Católica 3, 50009 Zaragoza, Spain; Aragón Health Sciences Institute, Zaragoza, Spain.
Maturitas. 2015 Mar;80(3):288-95. doi: 10.1016/j.maturitas.2014.12.004. Epub 2014 Dec 18.
The aim of this work is to study the prevalence of osteoporotic vertebral fractures in Spanish women over 45 years of age, based on the selection of a nationwide sample. An observational, cross-sectional, multicenter study was conducted during 2006, in all of Spain's regions. The sample analyzed was of 5000 individuals, representative of the female population over age 45 in Spain. A questionnaire was used to determine which factors are most often associated with vertebral fractures. We also assessed whether the Prevalent Vertebral Fracture Index, proposed by Vogt, is useful in indicating a possible osteoporotic vertebral fracture. Five hundred orthopedic surgeons, from various Spanish regions, were trained in different aspects of the study: inclusion and exclusion criteria, management of the risk factor questionnaire, and implementation of the Vogt questionnaire. The number of fracture cases was 1549 (31.79%). 528 Women (34.08%) had a single vertebral fracture, and 1021 (65.92%) had multiple vertebral fractures. The following factors were statistically significantly associated with vertebral fracture: age, late menarche, early menopause, diabetes mellitus, hyperparathyroidism, rheumatoid arthritis, height loss, daily physical activity, corticosteroid therapy, personal history of osteoporotic fracture and previous diagnosis of osteoporosis. The differences in Vogt score according to age and fracture status were statistically significant. The conclusion of the study is that vertebral osteoporotic fracture in the female Spanish population is frequent. The high prevalence in the Spanish population older than 60 years is probably related to malnutrition in the period from 1936 to 1952.
这项工作的目的是基于全国范围样本的选择，研究45岁以上西班牙女性骨质疏松性椎体骨折的患病率。2006年在西班牙所有地区开展了一项观察性、横断面、多中心研究。所分析的样本为5000名个体，代表了西班牙45岁以上的女性人群。使用问卷调查来确定哪些因素最常与椎体骨折相关。我们还评估了沃格特提出的椎体骨折患病率指数是否有助于指示可能的骨质疏松性椎体骨折。来自西班牙不同地区的500名骨科医生接受了该研究不同方面的培训：纳入和排除标准、危险因素问卷的管理以及沃格特问卷的实施。骨折病例数为1549例（31.79%）。528名女性（34.08%）有单一椎体骨折，1021名女性（65.92%）有多处椎体骨折。以下因素与椎体骨折在统计学上显著相关：年龄、初潮晚、绝经早、糖尿病、甲状旁腺功能亢进、类风湿关节炎、身高降低、日常体力活动、皮质类固醇治疗、骨质疏松性骨折个人史以及既往骨质疏松诊断。根据年龄和骨折状态的沃格特评分差异具有统计学意义。该研究的结论是，西班牙女性人群中的椎体骨质疏松性骨折很常见。60岁以上西班牙人群中的高患病率可能与1936年至1952年期间的营养不良有关。
