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中国雀形目鸟类中J亚群禽白血病病毒3'非翻译区的分子特征

Molecular characterization of 3'UTRs of J subgroup avian leukosis virus in passerine birds in China.

作者信息

Han Chunyan, Hao Ruijun, Liu Lanlan, Zeng Xiangwei

机构信息

College of Wildlife Resources, Northeast Forestry University, No. 26. Hexing Street, Harbin, 150040, China.

出版信息

Arch Virol. 2015 Mar;160(3):845-9. doi: 10.1007/s00705-014-2321-y. Epub 2015 Jan 11.

DOI:10.1007/s00705-014-2321-y
PMID:25577165
Abstract

To assess the status of avian leukosis virus subgroup J (ALV-J) infection in passerine birds in China, 365 passerine birds collected from northeast China from 2011 to 2013 were tested, and two ALV-J strains were isolated from yellow-browed warbler and marsh tit. The 3'untranslated regions (3'UTRs) of the two strains were amplified, cloned, and sequenced, with the results showing that the 3'UTRs of the two strains contained multiple mutations and deletions, which are similar to viral strains isolated from Chinese layer chickens. These results demonstrate the presence of ALV-J in passerine birds and reveal the molecular characteristics of the 3'UTRs of ALV-J from passerine birds.

摘要

为评估中国雀形目鸟类中禽白血病病毒J亚群(ALV-J)的感染状况,对2011年至2013年从中国东北地区采集的365只雀形目鸟类进行了检测,并从黄眉柳莺和沼泽山雀中分离出两株ALV-J毒株。对这两株毒株的3'非翻译区(3'UTRs)进行了扩增、克隆和测序,结果显示这两株毒株的3'UTRs存在多个突变和缺失,这与从中国蛋鸡中分离出的病毒毒株相似。这些结果证明了雀形目鸟类中存在ALV-J,并揭示了雀形目鸟类ALV-J 3'UTRs的分子特征。

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