Godber Olivia F, Phythian Clare J, Bosco Antonio, Ianniello Davide, Coles Gerald, Rinaldi Laura, Cringoli Giuseppe
University of Bristol, Division of Farm Animal Science, School of Clinical Veterinary Science, Langford House, Bristol BS40 5DU, United Kingdom.
University of Bristol, Division of Farm Animal Science, School of Clinical Veterinary Science, Langford House, Bristol BS40 5DU, United Kingdom.
Vet Parasitol. 2015 Jan 30;207(3-4):342-5. doi: 10.1016/j.vetpar.2014.12.029. Epub 2014 Dec 31.
Faecal egg counts (FECs) are used for detecting and quantifying nematode infections and are the basis for determining drug efficacy and anthelmintic resistance in faecal egg count reduction tests (FECRTs). Currently, several FEC techniques are available for detecting and quantifying eggs of sheep nematodes. A comparison of the egg counts from the FECPAK (with a minimum detection limit of 30 eggs per gram (epg)) and Mini-FLOTAC (with a minimum detection limit of 5 epg) showed better diagnostic performance with Mini-FLOTAC in terms of measurement error (level of over- or under-estimation of FEC) and precision (variability in FEC). A tendency to under-estimate FEC was observed with the FECPAK particularly at egg densities of less than 500 epg. It is concluded that Mini-FLOTAC is a reliable diagnostic tool offering reduced measurement error and a higher level of precision.
粪便虫卵计数（FECs）用于检测和定量线虫感染，是粪便虫卵计数减少试验（FECRTs）中确定药物疗效和抗蠕虫药耐药性的基础。目前，有几种FEC技术可用于检测和定量绵羊线虫的虫卵。对FECPAK（最低检测限为每克30个虫卵（epg））和Mini-FLOTAC（最低检测限为5 epg）的虫卵计数进行比较，结果显示，在测量误差（FEC高估或低估水平）和精密度（FEC变异性）方面，Mini-FLOTAC具有更好的诊断性能。尤其在虫卵密度低于500 epg时，观察到FECPAK有低估FEC的趋势。结论是，Mini-FLOTAC是一种可靠的诊断工具，可减少测量误差并提高精密度。
