Stievano Carlos Alexandre, Soares de Carvalho Neto Benjamim, de Souza Fábio Luiz, de Castro Laranjo Júnior Azuil, Saito Minori, Budib Luiz Jorge, Simões de Souza Auro Antônio, Haguihara Thiago, Moura Gonçalves Wildson, Diegues Paes Heleno
Servicio de Urología. Hospital Santa Marcelina. São Paulo. Brasil.
Arch Esp Urol. 2014 Dec;67(10):856-9.
We report a case of nonfunctioning giant adrenal cortical carcinoma undergoing complete resection.
We report the case and evolution of a woman who underwent resection of a giant adrenal carcinoma at Santa Marcelina Hospital.
A 49-year-old female presented with palpable mass in the right hypochondrium extending 5 cm down from the right costal margin. Abdominal CT Scan found a large mass occupying the right adrenal region with areas suggestive of necrosis, in close contact with the liver, pushing the right kidney inferiorly and extending to the midline. Biochemical tests to evaluate hormonal secretion resulted in levels within the normal range characteristic of a non-functioning adrenal neoplasm. The treatment of choice was resection of the abdominal mass; the surgical specimen greatest diameter was 21 cm and weighed 2106 grams. It was an adrenal cortical carcinoma.
Options for the treatment of adrenal cortical carcinoma showed no significant advances in recent decades and complete surgical resection remains the most effective treatment for adrenal cortical carcinoma, even in patients with bulky tumor masses.
我们报告一例接受完整切除的无功能性巨大肾上腺皮质癌病例。
我们报告一名在圣马塞利纳医院接受巨大肾上腺癌切除术的女性患者的病例及病情发展。
一名49岁女性，右季肋部可触及肿块，自右肋缘向下延伸5厘米。腹部CT扫描发现一个巨大肿块占据右肾上腺区域，有坏死区域，与肝脏紧密相连，将右肾向下推移并延伸至中线。评估激素分泌的生化检查结果显示在无功能性肾上腺肿瘤的正常范围内。首选治疗方法是切除腹部肿块；手术标本最大直径为21厘米，重2106克。这是一例肾上腺皮质癌。
近几十年来，肾上腺皮质癌的治疗选择没有显著进展，即使对于肿瘤体积较大的患者，完整的手术切除仍然是肾上腺皮质癌最有效的治疗方法。
