大鼠骨骼肌磷酸甘油酸变位酶cDNA序列
Sequence of rat skeletal muscle phosphoglycerate mutase cDNA.
作者信息
Castellà-Escolà J, Montoliu L, Pons G, Puigdomènech P, Cohen-Solal M, Carreras J, Rigau J, Climent F
机构信息
Unitat de Bioquímica, Facultat de Medicina, Universitat de Barcelona, Spain.
出版信息
Biochem Biophys Res Commun. 1989 Dec 29;165(3):1345-51. doi: 10.1016/0006-291x(89)92751-4.
A cDNA clone coding rat skeletal muscle phosphoglycerate mutase was isolated from a rat muscle lambda gt10 cDNA library and its sequence was determined. The deduced protein possesses 252 amino acids and is 94% homologous with respect to human muscle phosphoglycerate mutase. No amino acids changes occur at the active site and structural predictions suggest strong conformational homologies with other enzymes of the mutase family.
从大鼠肌肉λgt10 cDNA文库中分离出一个编码大鼠骨骼肌磷酸甘油酸变位酶的cDNA克隆，并测定了其序列。推导的蛋白质含有252个氨基酸，与人类肌肉磷酸甘油酸变位酶的同源性为94%。活性位点没有氨基酸变化，结构预测表明与变位酶家族的其他酶有很强的构象同源性。
Zotero 插件