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酿酒酵母磷酸甘油酸变位酶编码基因的序列。

Sequence of the gene encoding phosphoglycerate mutase from Saccharomyces cerevisiae.

作者信息

White M F, Fothergill-Gilmore L A

机构信息

Department of Biochemistry, University of Edinburgh, Scotland.

出版信息

FEBS Lett. 1988 Mar 14;229(2):383-7. doi: 10.1016/0014-5793(88)81161-x.

Abstract

The gene encoding yeast phosphoglycerate mutase was isolated, and its sequence was determined. The gene specifies a protein of 246 amino acids, and contains no introns. The sequence shows a strong codon bias. The upstream untranslated portion of the gene contains a CT-rich block such as is found in many highly expressed yeast genes, but does not have the associated CAAG sequence.

摘要

编码酵母磷酸甘油酸变位酶的基因被分离出来,并测定了其序列。该基因编码一个由246个氨基酸组成的蛋白质,且不含内含子。该序列显示出强烈的密码子偏好性。基因的上游非翻译区含有一个富含CT的区域,如在许多高表达的酵母基因中所发现的那样,但没有相关的CAAG序列。

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