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以不明原因不孕症为主要表现的乳糜泻:一例报告及文献综述

Unexplained infertility as primary presentation of celiac disease, a case report and literature review.

作者信息

Ghadir Mohammadreza, Iranikhah Abolfazl, Jandaghi Mahboubeh, Joukar Farahnaz, Sedigh-Rahimabadi Massih, Mansour-Ghanaei Fariborz

机构信息

Department of Gastroenterology, Qom University of Medical Sciences, Qom, Iran.

Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

出版信息

Iran J Reprod Med. 2011 Spring;9(2):135-40.

Abstract

BACKGROUND

Celiac sprue (gluten sensitive enteropathy) is an autoimmune disease which is hereditary and its pathology mainly bases on immunologic intolerance to gluten. It has a vast variety of signs and symptoms and its clinical features range from a silent disease to a typical gastrointestinal disorder. In this study we reviewed and summarized some other related issues about this disease and its relation with infertility.

CASE

The case is a 26 years old lady who had referred to a gynecologist because of infertility for 2 years and later it revealed that she has celiac sprue.

CONCLUSION

Screening for its silent or subtle types especially among suspicious cases such as unexplained infertility seems to be a cost effective action. Meanwhile, in time administration of a gluten-free diet can lead to an almost complete cure.

摘要

背景

乳糜泻(麸质敏感性肠病)是一种遗传性自身免疫性疾病,其病理主要基于对麸质的免疫不耐受。它有各种各样的体征和症状,临床特征从无症状疾病到典型的胃肠道疾病不等。在本研究中,我们回顾并总结了关于该疾病及其与不孕症关系的一些其他相关问题。

病例

该病例为一名26岁女性,因不孕2年转诊至妇科医生处,后来发现她患有乳糜泻。

结论

筛查其无症状或隐匿型,尤其是在不明原因不孕等可疑病例中,似乎是一项具有成本效益的措施。同时,及时给予无麸质饮食可导致几乎完全治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec5a/4216449/b9b0b859851d/ijrm-9-135-g001.jpg

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