Kurniali Peter C, Curry Stephanie, Brennan Keith W, Velletri Kim, Shaik Mohammed, Schwartz Kenneth A, McCormack Elise
Department of Medicine, Roger Williams Medical Center, Providence, RI, USA ; Department of Medicine, Boston University School of Medicine, Boston, MA, USA ; Division of Hematology Oncology, Michigan State University and Breslin Cancer Center, 401 W. Greenlawn Avenue, Lansing, MI 48910, USA.
Department of Medicine, Roger Williams Medical Center, Providence, RI, USA ; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Anemia. 2014;2014:634582. doi: 10.1155/2014/634582. Epub 2014 Dec 21.
Hospitalized patients frequently have considerable volumes of blood removed for diagnostic testing which could lead to the development of hospital-acquired anemia. Low hemoglobin levels during hospitalization may result in significant morbidity for patients with underlying cardiorespiratory and other illnesses. We performed a retrospective study and data was collected using a chart review facilitated through an electronic medical record. A total of 479 patients who were not anemic during admission were included in analysis. In our study, we investigated the incidence of HAA and found that, between admission and discharge, 65% of patients dropped their hemoglobin by 1.0 g/dL or more, and 49% of patients developed anemia. We also found that the decrease in hemoglobin between admission and discharge did not differ significantly with smaller phlebotomy tubes. In multivariate analysis, we found that patients with longer hospitalization and those with lower BMI are at higher risk of developing HAA. In conclusion, our study confirms that hospital-acquired anemia is common. More aggressive strategies such as reducing the frequency of blood draws and expanding the use of smaller volume tubes for other laboratory panels may be helpful in reducing the incidence of HAA during hospitalization.
住院患者经常会因诊断检测而抽取大量血液，这可能导致医院获得性贫血的发生。住院期间血红蛋白水平低可能会给患有潜在心肺疾病和其他疾病的患者带来显著的发病率。我们进行了一项回顾性研究，并通过电子病历进行图表审查来收集数据。共有479名入院时无贫血的患者纳入分析。在我们的研究中，我们调查了医院获得性贫血的发生率，发现入院至出院期间，65%的患者血红蛋白下降了1.0g/dL或更多，49%的患者发生了贫血。我们还发现，使用较小采血管时，入院至出院期间血红蛋白的下降没有显著差异。在多变量分析中，我们发现住院时间较长和体重指数较低的患者发生医院获得性贫血的风险较高。总之，我们的研究证实医院获得性贫血很常见。更积极的策略，如减少抽血频率和扩大使用较小采血量的采血管用于其他实验室检测项目，可能有助于降低住院期间医院获得性贫血的发生率。
