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腰椎间盘突出症患者椎间盘切除术后疼痛评分与椎间盘高度变化的相关性:系统评价和荟萃分析。

Correlation between Pain Scores and Disc Height Changes after Discectomy in Patients with Lumbar Disc Herniation: A Systematic Review and Meta-Analysis.

机构信息

Department of Spine Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.

出版信息

Comput Intell Neurosci. 2022 Aug 5;2022:2580004. doi: 10.1155/2022/2580004. eCollection 2022.

Abstract

BACKGROUND

Surgery can reduce and improve lumbar disc herniation, but some patients still have pain after surgery, and the relationship between lumbar disc height and pain after surgery is still unclear.

OBJECTIVE

The main objective is to investigate the relationship between lumbar disc height and postoperative pain.

METHODS

We searched Pubmed, Web of Science, the Cochrane library, and Embase online for cohort studies or RCT studies on discectomy and assessed the quality of the included articles using the Newcastle-Ottawa Scale (NOS scale), with disc height (DH) and postoperative back pain as the main clinical outcome indicators, and the correlation coefficient between DH and back pain as the statistic to assess the pooled effect size.

RESULTS

10 kinds of literature were included in this study for quantitative analysis. A total of 589 patients participated in the study. The follow-up time was between 1 and 2.3 years. Meta-analysis showed that after surgery, the relief of back pain was statistically significant ( = -2.57, 95% CI (-3.10,-2.04),  = -9.570, < 0.0001), the reduction of disc height was statistically significant ( = -0.82, 95% CI (-1.11, -0.52),  = -5.477, < 0.0001), the combined value of correlation coefficient Fisher's value was 0.33, 95% CI (0.25,0.42), with statistical significance ( < 0.00001), suggesting that the degree of back pain after surgery showed a moderate positive correlation with disc height in the short term. . After discectomy, the degree of pain is relieved, the disc height is reduced, and low back pain in the short term and disc height showed a moderate positive correlation, but the long-term correlation remains to be studied in depth.

摘要

背景

手术可以减轻和改善腰椎间盘突出症,但有些患者术后仍有疼痛,腰椎间盘高度与术后疼痛的关系尚不清楚。

目的

主要目的是探讨腰椎间盘高度与术后疼痛的关系。

方法

我们在 Pubmed、Web of Science、Cochrane 图书馆和 Embase 在线上搜索了关于椎间盘切除术的队列研究或 RCT 研究,并使用纽卡斯尔-渥太华量表(NOS 量表)评估纳入文章的质量,以椎间盘高度(DH)和术后腰痛为主要临床结局指标,DH 与腰痛之间的相关系数作为统计量评估汇总效应量。

结果

本研究共纳入 10 种文献进行定量分析。共有 589 例患者参与研究。随访时间为 1 至 2.3 年。Meta 分析显示,术后腰痛缓解有统计学意义( = -2.57,95%CI(-3.10,-2.04), = -9.570, < 0.0001),椎间盘高度降低有统计学意义( = -0.82,95%CI(-1.11,-0.52), = -5.477, < 0.0001),相关系数 Fisher 合并值为 0.33,95%CI(0.25,0.42),有统计学意义( < 0.00001),提示术后腰痛程度与短期椎间盘高度呈中度正相关。. 椎间盘切除术后,疼痛程度减轻,椎间盘高度降低,短期内腰痛与椎间盘高度呈中度正相关,但长期相关性仍需深入研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85f/9410963/9f41c26b642e/CIN2022-2580004.001.jpg

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