Cowen B S, Wideman R F, Rothenbacher H, Braune M O
Avian Dis. 1987 Apr-Jun;31(2):392-7.
A significant outbreak of avian urolithiasis was observed on a large commercial egg farm. From the initial outbreak site (a single laying house), the incidence of urolithiasis slowly spread in the ensuing months to numerous other laying houses. Increasing mortality associated with urolithiasis commenced during late growout to early lay and then leveled off when egg production peaked. At the height of the outbreak, mortality was typically 0.5% per week; 75% of this mortality was due to urolithiasis. The clinical and pathologic features of this condition are described. Both infectious bronchitis virus (IBV) and fowl adenoviruses were isolated from organ homogenates of sampled birds. A clone of the IBV strain was found to induce nephritis in specific-pathogen-free white leghorns.
在一个大型商业蛋鸡场观察到了一起严重的禽尿石症疫情。从最初的疫情爆发地点（一个单栋产蛋鸡舍）开始，尿石症的发病率在随后的几个月里缓慢蔓延到许多其他产蛋鸡舍。与尿石症相关的死亡率在育成后期到产蛋初期开始上升，然后在产蛋量达到峰值时趋于平稳。在疫情高峰期，死亡率通常为每周0.5%；其中75%的死亡是由尿石症导致的。描述了这种病症的临床和病理特征。从采样鸡的器官匀浆中分离出了传染性支气管炎病毒（IBV）和禽腺病毒。发现一株IBV毒株的克隆可在无特定病原体的白来航鸡中诱发肾炎。
