来自沙特阿拉伯生长的大戟叶的化学成分。
Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia.
作者信息
Abdel-Sattar Essam, Abou-Hussein Dina, Petereit Frank
机构信息
Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt ; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
出版信息
Pharmacognosy Res. 2015 Jan-Mar;7(1):14-7. doi: 10.4103/0974-8490.147136.
Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.
对大戟叶氯仿提取物的研究导致分离出三种化合物
大戟醇（1）、α-谷甾醇（2）和豆甾醇（3）。它们的结构通过一维和二维核磁共振以及与报道数据的比较得以阐明。化合物1-3在体外对人宫颈腺癌（Hela）表现出细胞毒性，其中化合物1表现出最佳活性。
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