Akhondi Hossein
Georgetown University Medical Center, Washington, DC, USA.
Int J Biomed Sci. 2014 Dec;10(4):282-6.
Sloughing esophagitis, also known as esophagitis dissecans superficialis, is a very rare and underdiagnosed entity with unknown incidence rate. It can be associated with bullous dermatoses and medications such as central nervous system depressants and those causing esophageal injury.
A 55-years-old woman was recovering from renal failure due to rhabdomyolysis when she developed dysphagia and odynophagia. Esophagogastroduodenoscopy with biopsy was performed for suspected bullous pemphigus and confirmed sloughing esophagitis. She improved with intravenous steroids.
Sloughing Esophagitis should enter our differential diagnosis more frequently. It is mostly a benign, self-limiting process but when associated with bullous dermatoses will require steroid treatment.
剥脱性食管炎,又称浅表性食管层状剥脱炎,是一种非常罕见且诊断不足的疾病,发病率未知。它可能与大疱性皮肤病以及中枢神经系统抑制剂等药物和那些导致食管损伤的药物有关。
一名55岁女性因横纹肌溶解导致肾衰竭正在康复,此时出现吞咽困难和吞咽痛。因疑似大疱性天疱疮进行了食管胃十二指肠镜检查及活检,确诊为剥脱性食管炎。她通过静脉注射类固醇后病情好转。
剥脱性食管炎应更频繁地纳入我们的鉴别诊断。它大多是一个良性的、自限性过程,但与大疱性皮肤病相关时需要类固醇治疗。