Lima Ana Catarina, Mano João F
3B's Research Group - Biomaterials, Biodegradables & Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Ave Park, 4806-909 Taipas, Guimarães, Portugal.
Nanomedicine (Lond). 2015 Jan;10(2):271-97. doi: 10.2217/nnm.14.175.
The properties of surfaces define the acceptance and integration of biomaterials in vivo, as well as the material's efficiency when used at research or manufacturing levels. The presence of micro/nano-topographical structures and low surface energies could bring several advantages when highly repellent surfaces are employed in the biomedical field. Biomimetic superhydrophobic surfaces have been explored for diverse applications: as an intrinsic characteristic of biomaterials to be implanted; as materials that exhibit special interactions with biological entities; or to be used in ex vivo applications. This article aims to focus on the main motivations and requirements in the biomedical field that pushed for the utilization of superhydrophobic surfaces as suitable alternatives, as well as the great evolution of applications that have emerged in the last few years.
表面特性决定了生物材料在体内的接受程度和整合情况，以及该材料在研究或制造层面使用时的效率。当在生物医学领域采用高拒水表面时，微/纳米拓扑结构的存在和低表面能可能会带来诸多优势。仿生超疏水表面已被探索用于多种应用：作为植入生物材料的固有特性；作为与生物实体表现出特殊相互作用的材料；或用于体外应用。本文旨在聚焦生物医学领域推动将超疏水表面用作合适替代方案的主要动机和要求，以及过去几年中出现的应用的巨大发展。
