Hertelyova Z, Salaj R, Chmelarova A, Dombrovsky P, Dvorakova M C, Kruzliak P
Department of Experimental Medicine, Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovak Republic.
Department of Pathophysiology, Faculty of Medicine, Pavol Jozef Safarik University, Kosice, Slovak Republic.
J Endocrinol Invest. 2016 Jul;39(7):769-78. doi: 10.1007/s40618-015-0240-8. Epub 2015 Jan 20.
Abdominal obesity is associated with high plasma triglyceride and with low plasma high-density lipoprotein cholesterol levels.
Objective of the study was to find an association between plasma lipid and lipoprotein levels and anthropometric parameters in abdominal obesity in Slovakian university students. Lipid profile and anthropometric parameters of obesity were studied in a sample of 419 probands, including 137 men and 282 women.
Males had higher values of non-high-density lipoprotein cholesterol (non-HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) and very low-density lipoprotein cholesterol (VLDL-C) than females, but these differences were not significant. Females had significantly (P < 0.05) higher TC and HDL-C (P < 0.001) than males. In comparison, all anthropometric parameters in the males were significantly (P < 0.001) higher than in the females. A positive correlation between non-HDL-C, TG, VLDL-C and anthropometric parameters (BMI, WC, WHR, WHtR) was found at P < 0.001. LDL was positively correlated with BMI, WCF, WHtR and TC with BMI, WHtR at P < 0.001. We also observed a correlation between TC-WCF and LDL-WHR at P < 0.01. A negative correlation was found between HDL and all monitored anthropometric parameters at P < 0.001. On the other hand, no correlation between TC and WHR was detected.
This study shows an association between plasma lipid and lipoprotein levels and anthropometric parameters in abdominal obesity in young people, predominantly university students.
腹部肥胖与高血浆甘油三酯及低血浆高密度脂蛋白胆固醇水平相关。
本研究的目的是在斯洛伐克大学生的腹部肥胖人群中，寻找血浆脂质和脂蛋白水平与人体测量学参数之间的关联。对419名受试者（包括137名男性和282名女性）的血脂谱和肥胖相关人体测量学参数进行了研究。
男性的非高密度脂蛋白胆固醇（non-HDL-C）、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（TG）和极低密度脂蛋白胆固醇（VLDL-C）水平高于女性，但这些差异无统计学意义。女性的总胆固醇（TC）和高密度脂蛋白胆固醇（HDL-C）水平显著高于男性（P < 0.05和P < 0.001）。相比之下，男性的所有人体测量学参数均显著高于女性（P < 0.001）。发现non-HDL-C、TG、VLDL-C与人体测量学参数（BMI、腰围、腰臀比、腰高比）之间呈正相关，P < 0.001。LDL与BMI、腰围、腰高比呈正相关，TC与BMI、腰高比呈正相关，P < 0.001。我们还观察到TC-腰围和LDL-腰臀比之间在P < 0.01时有相关性。HDL与所有监测的人体测量学参数之间呈负相关，P < 0.001。另一方面，未检测到TC与腰臀比之间的相关性。
本研究表明，在年轻人（主要是大学生）的腹部肥胖中，血浆脂质和脂蛋白水平与人体测量学参数之间存在关联。
