Melato M, Peruzzo P, Laurino L, Valente M, Tussoni A
Klin Med (Mosk). 1989 Nov;67(11):47-9.
The findings at 26.879 autopsies, that is 70% of all the deaths registered in the Province of Trieste, obtained at the Institute of Pathologic Anatomy and Histology of Trieste from 1976 to 1985 were studied. Liver cancer showed in the Province the World Standardized Incidence Rate (WR) of 1.87 (females) and 12.78 (males), one of the highest ever observed in nonendemic areas. In view of close association between cancer of the liver and cirrhosis (88%), the authors studied the most important etiological factors of cirrhosis in the region, i.e. hepatitis B and alcohol abuse. Some effective measures are suggested to decrease the incidence of cirrhosis and eventually cancer of the liver.
对的里雅斯特病理解剖与组织学研究所1976年至1985年期间进行的26879例尸检结果进行了研究,这些尸检占的里雅斯特省所有登记死亡人数的70%。该省肝癌的世界标准化发病率(WR),女性为1.87,男性为12.78,是在非流行地区观察到的最高发病率之一。鉴于肝癌与肝硬化之间的密切关联(88%),作者研究了该地区肝硬化最重要的病因,即乙型肝炎和酗酒。文中提出了一些有效措施以降低肝硬化以及最终肝癌的发病率。