Abidi Nadia, Foering Kristen, Sahu Joya
Department of Dermatology, Jefferson Medical College, Thomas Jefferson University, 833 Chestnut Street, Suite 740, Philadelphia, PA 19107, USA.
Case Rep Dermatol Med. 2014;2014:452720. doi: 10.1155/2014/452720. Epub 2014 Dec 31.
Acquired brachial cutaneous dyschromatosis is an acquired pigmentary disorder that has been described in only 20 patients but likely affects many more. This case of a man with acquired brachial cutaneous dyschromatosis is unique as most reports are in women. We report the case of a 60-year-old male who presents with an asymptomatic eruption characterized by hyperpigmented and telangiectatic macules coalescing into patches on the bilateral extensor aspects of the forearms which is consistent clinically and histopathologically with acquired brachial cutaneous dyschromatosis. Given its presence in patients with clinical evidence of chronic sun exposure and its histopathological finding of solar elastosis, acquired brachial cutaneous dyschromatosis is likely a disorder caused by cumulative UV damage. However, a possible association between angiotensin-converting enzyme inhibitors and acquired brachial cutaneous dyschromatosis exists. Further investigation is needed to elucidate both the pathogenesis of the disorder and forms of effective management. Treatment of the disorder should begin with current established treatments for disorders of dyspigmentation.
获得性臂部皮肤色素沉着异常是一种获得性色素沉着紊乱疾病，仅在20例患者中被描述过，但可能影响更多人。该例患有获得性臂部皮肤色素沉着异常的男性患者很独特，因为大多数报告的病例是女性。我们报告一例60岁男性患者，其表现为无症状性皮疹，特征为色素沉着过度和毛细血管扩张性斑疹融合成斑片，位于双侧前臂伸侧，临床和组织病理学表现均符合获得性臂部皮肤色素沉着异常。鉴于其在有慢性日晒临床证据的患者中出现，以及其组织病理学发现有日光性弹力组织变性，获得性臂部皮肤色素沉着异常可能是一种由累积紫外线损伤引起的疾病。然而，血管紧张素转换酶抑制剂与获得性臂部皮肤色素沉着异常之间可能存在关联。需要进一步研究以阐明该疾病的发病机制和有效的治疗方式。该疾病的治疗应从目前已确立的色素沉着紊乱疾病治疗方法开始。
