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慢性硬膜下血肿钻孔冲洗术与开颅手术的比较:患者预后及成本分析

Burr hole washout versus craniotomy for chronic subdural hematoma: patient outcome and cost analysis.

作者信息

Regan Jacqueline M, Worley Emmagene, Shelburne Christopher, Pullarkat Ranjit, Watson Joseph C

机构信息

University of Michigan, Ann Arbor, MI, United States of America.

Virginia Commonwealth University, Inova Campus, Falls Church, VA, United States of America.

出版信息

PLoS One. 2015 Jan 22;10(1):e0115085. doi: 10.1371/journal.pone.0115085. eCollection 2015.

Abstract

Chronic subdural hematomas (CSDH), which are frequently encountered in neurosurgical practice, are, in the majority of cases, ideally treated with surgical drainage. Despite this common practice, there is still controversy surrounding the best surgical procedure. With lack of clear evidence of a superior technique, surgeons are free to base the decision on other factors that are not related to patient care. A retrospective chart review of 119 patients requiring surgical drainage of CSDH was conducted at a large tertiary care center over a three-year period. Of the cases reviewed, 58 patients underwent craniotomy, while 61 patients underwent burr hole washout. The study focused on re-operation rates, mortality, and morbidity, as measured by Glasgow coma scores (GCS), discharge Rankin disability scores, and discharge disposition. Secondary endpoints included length of stay and cost of procedure. Burr hole washout was superior to craniotomy with respect to patient outcome, length of stay and recurrence rates. In both study groups, patients required additional surgical procedures (6.6% of burr hole patients and 24.1% of craniotomy patients) (P = 0.0156). Of the patients treated with craniotomy, 51.7% were discharged home, whereas 65.6% of the burr hole patients were discharged home. Patients who underwent burr hole washout spent a mean of 78.8 minutes in the operating suite while the patients undergoing craniotomy spent 129.4 minutes (P < 0.001). The difference in mean cost per patient, based solely on operating time, was $2,828 (P < 0.001). This does not include the further cost due to additional procedures and hospital stay. The mean length of stay after surgical intervention was 3 days longer for the craniotomy group (P = 0.0465). Based on this retrospective study, burr hole washout is superior for both patients' clinical and financial outcome; however, prospective long-term multicenter clinical studies are required to verify these findings.

摘要

慢性硬膜下血肿(CSDH)在神经外科实践中经常遇到,在大多数情况下,理想的治疗方法是手术引流。尽管有这种常见的做法,但关于最佳手术方法仍存在争议。由于缺乏 superior 技术的明确证据,外科医生可以自由地根据与患者护理无关的其他因素做出决定。在一家大型三级医疗中心对119例需要手术引流 CSDH 的患者进行了为期三年的回顾性图表审查。在审查的病例中,58例患者接受了开颅手术,而61例患者接受了钻孔冲洗术。该研究重点关注再次手术率、死亡率和发病率,通过格拉斯哥昏迷评分(GCS)、出院 Rankin 残疾评分和出院处置情况来衡量。次要终点包括住院时间和手术费用。在患者预后、住院时间和复发率方面,钻孔冲洗术优于开颅手术。在两个研究组中,患者都需要额外的手术(钻孔患者的6.6%和开颅患者的24.1%)(P = 0.0156)。接受开颅手术的患者中,51.7%出院回家,而钻孔患者的这一比例为65.6%。接受钻孔冲洗术的患者在手术室平均花费78.8分钟,而接受开颅手术的患者花费129.4分钟(P < 0.001)。仅基于手术时间,每位患者的平均费用差异为2828美元(P < 0.001)。这还不包括额外手术和住院的进一步费用。开颅手术组术后平均住院时间长3天(P = 0.0465)。基于这项回顾性研究,钻孔冲洗术在患者的临床和经济预后方面都更具优势;然而,需要前瞻性的长期多中心临床研究来验证这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b760/4303411/bba37c21b740/pone.0115085.g001.jpg

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