Wu Wei-Wen, Tsai Shao-Yu, Liang Shu-Yuan, Liu Chieh-Yu, Jou Shiann-Tarng, Berry Donna L
National Taipei University of Nursing and Health Sciences, Taipei, Taiwan
National Taiwan University, Taipei, Taiwan.
J Pediatr Oncol Nurs. 2015 Sep-Oct;32(5):304-13. doi: 10.1177/1043454214563758. Epub 2015 Jan 22.
Understanding how cancer symptom distress and resilience contribute to quality of life (QoL) in adolescent cancer and may potentially help these patients achieve better health-related outcomes. The objective of this study was to describe cancer symptom distress, QoL, and resilience in adolescents with cancer and to determine whether resilience is a mediating variable. Forty adolescent cancer patients were recruited, and data were collected via a demographic questionnaire, the Cancer Symptom Distress Scale, the Resilience Scale, and the Minneapolis-Manchester Quality of Life Scale. Pearson's correlation, multiple regressions, and the Sobel test were conducted. Both resilience and cancer symptom distress were regressed against QoL, accounting for 62.1% of observed variation in QoL scores. The bootstrap result estimated the true indirect effect between -.0189 and -.0024, with a 95% confidence interval. Resilience mediates the relationship between cancer symptom distress and QoL. Clinical use of a resilience measure, for example to use in developing and evaluating interventions focused on enhancing resilience, may be practical for nurses.
了解癌症症状困扰和心理韧性如何影响青少年癌症患者的生活质量（QoL），并可能有助于这些患者获得更好的健康相关结果。本研究的目的是描述癌症青少年患者的癌症症状困扰、生活质量和心理韧性，并确定心理韧性是否为中介变量。招募了40名青少年癌症患者，通过人口统计学问卷、癌症症状困扰量表、心理韧性量表和明尼阿波利斯-曼彻斯特生活质量量表收集数据。进行了Pearson相关性分析、多元回归分析和Sobel检验。心理韧性和癌症症状困扰均与生活质量进行回归分析，解释了生活质量得分中62.1%的观察变异。自抽样结果估计真实间接效应在-.0189至-.0024之间，置信区间为95%。心理韧性在癌症症状困扰和生活质量之间起中介作用。例如，在制定和评估旨在增强心理韧性的干预措施时使用心理韧性测量方法，对护士来说可能具有实际意义。
