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来自反折肉珊瑚(埃伦伯格)的新孕甾烷糖苷衍生物。

New pregnane glycoside derivative from Caralluma retrospiciens (Ehrenb).

作者信息

Elsebai Mahmoud Fahmi, Mohamed Ietidal El-Tahir

机构信息

a Department of Pharmacognosy , Faculty of Pharmacy, Mansoura University , Mansoura , Egypt.

出版信息

Nat Prod Res. 2015;29(15):1426-31. doi: 10.1080/14786419.2014.1003186. Epub 2015 Jan 23.

Abstract

Retrospinoside (1) is a new polyoxy pregnane glycoside which was isolated and characterised from the aerial parts of Caralluma retrospiciens (Ehrenb.) N. E. Br., family Apocynaceae. The structure was established as 3-O-[β-D-glucopyranosyl-(1 → 4)-β-D-(3-O-methyl-6-desoxygalactopyranosy)]-14,15,20-trihydroxy-4β-pregnane. Its structural elucidation was performed through extensive spectroscopic measurements including 1D- and 2D-NMR, and HRMS, in addition to chemical methods.

摘要

逆刺参苷(1)是一种新的多氧孕甾烷糖苷,从夹竹桃科植物逆刺牛角瓜(Ehrenb.)N. E. Br. 的地上部分分离得到并进行了表征。其结构确定为3-O-[β-D-吡喃葡萄糖基-(1→4)-β-D-(3-O-甲基-6-脱氧吡喃半乳糖基)]-14,15,20-三羟基-4β-孕甾烷。除化学方法外,还通过广泛的光谱测量,包括1D-和2D-NMR以及HRMS对其结构进行了阐明。

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