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急性憩室炎及其并发症的管理。

Management of acute diverticulitis and its complications.

作者信息

Welbourn Hannah L, Hartley John E

机构信息

Academic Surgical Unit, Castle Hill Hospital, Castle Road, Cottingham, HU16 5JQ UK.

出版信息

Indian J Surg. 2014 Dec;76(6):429-35. doi: 10.1007/s12262-014-1086-6. Epub 2014 May 23.

Abstract

Colonic diverticular disease is a common condition, and around a quarter of people affected by it will experience acute symptoms at some time. The most common presentation is uncomplicated acute diverticulitis that can be managed conservatively with bowel rest and antibiotics. However, some patients will present with diverticular abscesses or purulent or faeculent peritonitis due to perforated diverticular disease. Whilst most mesocolic abscesses can be managed with percutaneous drainage alone, pelvic abscesses are associated with a higher rate of future complications and usually require percutaneous drainage followed by interval sigmoid resection. Patients who require emergency surgery for complicated acute diverticulitis most commonly undergo a Hartmann's procedure, although resection with primary anastomosis and laparoscopic peritoneal lavage have emerged as alternative treatment options for patients with purulent peritonitis in recent years. However, robust evidence from randomized trials is lacking for these alternative procedures, and the studies that have reported good outcomes from them have included carefully selected patient groups. There has been a move away from recommending elective prophylactic colectomy after two episodes of acute diverticulitis in the light of evidence that most patients will not experience a significant recurrence of their symptoms; elective surgery is indicated for those with ongoing symptoms, pelvic abscesses, complications-such as fistulating disease, strictures or recurrent diverticular bleeding-and those who are at high risk of perforation during future episodes, for example, due to immunosuppression, chronic renal failure or collagen-vascular diseases.

摘要

结肠憩室病是一种常见疾病,约四分之一的患者在某些时候会出现急性症状。最常见的表现是单纯性急性憩室炎,可通过肠道休息和使用抗生素进行保守治疗。然而,一些患者会因憩室病穿孔而出现憩室脓肿或脓性或粪性腹膜炎。虽然大多数结肠系膜脓肿仅通过经皮引流即可处理,但盆腔脓肿未来并发症的发生率较高,通常需要先进行经皮引流,然后择期行乙状结肠切除术。因复杂性急性憩室炎需要急诊手术的患者最常接受哈特曼手术,不过近年来,对于脓性腹膜炎患者,一期吻合切除术和腹腔镜腹膜灌洗已成为替代治疗选择。然而,这些替代手术缺乏来自随机试验的有力证据,且报道这些手术有良好效果的研究纳入的是经过精心挑选的患者群体。鉴于大多数患者症状不会显著复发的证据,目前已不再建议在发生两次急性憩室炎后进行择期预防性结肠切除术;对于有持续症状、盆腔脓肿、并发症(如瘘管形成、狭窄或复发性憩室出血)以及未来发作时有穿孔高风险的患者(例如,由于免疫抑制、慢性肾衰竭或胶原血管疾病),则需进行择期手术。

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