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呼吸暂停低通气指数(AHI)对评估阻塞性睡眠呼吸暂停严重程度是否足够?

Does AHI Value Enough for Evaluating the Obstructive Sleep Apnea Severity?

作者信息

Dündar Yusuf, Saylam Güleser, Tatar Emel Çadallı, Özdek Ali, Korkmaz Hakan, Fırat Hikmet, Ardıç Sadık

机构信息

Department of Otolaryngology, Ministry of Health, Idil Community Hospital, Sırnak, Turkey.

Department of Otolaryngology, Ministry of Health, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey.

出版信息

Indian J Otolaryngol Head Neck Surg. 2015 Mar;67(Suppl 1):16-20. doi: 10.1007/s12070-014-0722-6. Epub 2014 Apr 19.

Abstract

Obstructive sleep apnea/hypopnea syndrome (OSAHS) is an important and more common public health problem with increasing incidence. Polysomonography (PSG) is the gold standard test in OSAHS diagnosis. Apnea-hypopnea index (AHI) is the main parameter of PSG, which is correlated with OSAHS severity. The main complaint of OSAHS patients is daytime sleepiness and the Epworth Sleepiness Scale (ESS) used for evaluation of disease severity. The correlation of AHI with daytime sleepiness and ESS is well known. But there are many patients, which have uncorrelated daytime sleepiness with AHI. This data calls this hypothesis; Are there any other parameters which may affect daytime sleepiness. 648 patients with complaining of snoring and apnea were evaluated by polysomnography and anthropometric measurements. The cut-off value of ESS was accepted 10 as an indicator of severe daytime sleepiness. Patients were divided to groups with the aim of homogenization, according to AHI values. The patients with similar AHI values were analyzed according to their ESS scores. BMI and neck circumference were elevated in daytime sleepiness patients. The nocturnal hypoxemia markers; apnea number/index, maximum duration of apnea, at least SO2 concentration, duration of SO2 less than 90 % were much effected in the group of daytime sleepiness. Beside the fact that our research, AHI is not enough for predicting the daytime sleepiness; anthropometric measurements and the nocturnal hypoxemia markers should be evaluated.

摘要

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是一个重要且日益常见的公共卫生问题,发病率不断上升。多导睡眠图(PSG)是OSAHS诊断的金标准测试。呼吸暂停低通气指数(AHI)是PSG的主要参数,与OSAHS的严重程度相关。OSAHS患者的主要症状是日间嗜睡,Epworth嗜睡量表(ESS)用于评估疾病严重程度。AHI与日间嗜睡和ESS之间的相关性是众所周知的。但有许多患者的日间嗜睡与AHI不相关。这些数据引发了这样一个假设:是否有其他参数可能影响日间嗜睡?对648例主诉打鼾和呼吸暂停的患者进行了多导睡眠图和人体测量评估。ESS的临界值被设定为10,作为严重日间嗜睡的指标。根据AHI值将患者分组以实现同质化。对AHI值相似的患者根据其ESS评分进行分析。日间嗜睡患者的体重指数(BMI)和颈围升高。夜间低氧血症指标,如呼吸暂停次数/指数、最长呼吸暂停持续时间、最低血氧饱和度(SO2)浓度、SO2低于90%的持续时间,在日间嗜睡组中受到的影响更大。除了我们的研究之外,AHI不足以预测日间嗜睡;还应评估人体测量指标和夜间低氧血症指标。

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