Shikrakawa M, Shinbori H, Nakanishi K, Ogawa T, Fujita M, Wada T, Okamoto H
Nihon Shishubyo Gakkai Kaishi. 1989 Sep;31(3):882-8. doi: 10.2329/perio.31.882.
The purpose of this study was to evaluate the effect of implants of granular hydroxyapatite (HAP). HAP was implanted into twenty-five vertical bone defects of twenty-one patients as bone graft material. Various clinical and radiographic examinations were performed postoperatively over a twelve month period. Redness and swelling of the gingiva, gingival bleeding, postoperative pain and increased tooth mobility developed transiently, but they all recovered in time. Open wounds and out-flow of HAP disappeared within the first month. After twelve months, mean probing depth decrease was 3.7 mm and clinical attachment gain was 2.5 mm. In all cases there was radiographic evidence of alveolar bone repair. These results suggest that HAP is clinically effective as a bone graft in periodontal therapy.
本研究的目的是评估颗粒状羟基磷灰石（HAP）植入物的效果。将HAP作为骨移植材料植入21例患者的25个垂直骨缺损处。术后在12个月期间进行了各种临床和影像学检查。牙龈出现短暂的发红、肿胀、牙龈出血、术后疼痛和牙齿松动增加，但均及时恢复。开放性伤口和HAP流出在第一个月内消失。12个月后，平均探诊深度减少3.7毫米，临床附着获得2.5毫米。所有病例均有牙槽骨修复的影像学证据。这些结果表明，HAP在牙周治疗中作为骨移植材料在临床上是有效的。
