Dipartimento di Ingegneria Industriale e dell'Informazione, Università di Pavia, Via Ferrata 5A, 27100 Pavia, Italy.
Lab Chip. 2015 Mar 7;15(5):1262-6. doi: 10.1039/c4lc01496k.
We present a novel optofluidic device for real-time sorting on the basis of cell mechanical properties, measured by optical stretching. The whole mechanism, based on optical forces, does not hamper the viability of the tested cells, which can be used for further analysis. The device effectiveness is demonstrated by extracting a sample population enriched with highly metastatic cells from a heterogeneous cell mixture.
我们提出了一种基于光学拉伸测量细胞力学特性的新型光流控实时分选装置。整个基于光学力的机制不会影响被测试细胞的生存能力，这些细胞可以用于进一步的分析。该装置的有效性通过从异质细胞混合物中提取富含高转移性细胞的样本群来证明。
