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比较从普通公众中得出的不同类型QALY增益的支付意愿值。

Comparing WTP values of different types of QALY gain elicited from the general public.

作者信息

Pennington Mark, Baker Rachel, Brouwer Werner, Mason Helen, Hansen Dorte Gyrd, Robinson Angela, Donaldson Cam

机构信息

London School of Hygiene & Tropical Medicine, London, UK.

出版信息

Health Econ. 2015 Mar;24(3):280-93. doi: 10.1002/hec.3018. Epub 2013 Dec 11.

Abstract

BACKGROUND

The appropriate thresholds for decisions on the cost-effectiveness of medical interventions remain controversial, especially in 'end-of-life' situations. Evidence of the values placed on different types of health gain by the general public is limited.

METHODS

Across nine European countries, 17,657 people were presented with different hypothetical health scenarios each involving a gain of one quality adjusted life year (QALY) and asked about their willingness to pay (WTP) for that gain. The questions included quality of life (QoL) enhancing and life extending health gains, and a scenario where respondents faced imminent, premature death.

RESULTS

The mean WTP values for a one-QALY gain composed of QoL improvements were modest (PPP$11,000). When comparing QALY gains obtained in the near future, the valuation of life extension exceeded the valuation of QoL enhancing gains (mean WTP PPP$19,000 for a scenario in which a coma is avoided). The mean WTP values were higher still when respondents faced imminent, premature death (PPP$29,000).

CONCLUSIONS

Evidence from the largest survey on the value of health gains by the general public indicated a higher value for life extending gains compared with QoL enhancing gains. A further modest premium may be indicated for life extension when facing imminent, premature death.

摘要

背景

对于医疗干预措施成本效益决策的适当阈值仍存在争议,尤其是在“临终”情况下。关于普通公众对不同类型健康收益所赋予价值的证据有限。

方法

在九个欧洲国家,向17657人展示了不同的假设健康情景,每个情景都涉及获得一个质量调整生命年(QALY),并询问他们为该收益的支付意愿(WTP)。问题包括提高生活质量(QoL)和延长生命的健康收益,以及受访者面临即将到来的过早死亡的情景。

结果

由生活质量改善构成的一个QALY收益的平均支付意愿值适中(购买力平价11000美元)。在比较近期获得的QALY收益时,延长生命的估值超过了提高生活质量收益的估值(避免昏迷情景下的平均支付意愿购买力平价19000美元)。当受访者面临即将到来的过早死亡时,平均支付意愿值更高(购买力平价29000美元)。

结论

来自关于普通公众健康收益价值的最大规模调查的证据表明,与提高生活质量的收益相比,延长生命的收益价值更高。当面临即将到来的过早死亡时,延长生命可能还会有适度的溢价。

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