Figueiredo Mario Luis Garcia de, Figueiredo Luiz Tadeu Moraes
Instituto Evandro Chagas, Belém, PA, Brazil.
Centro de Pesquisa em Virologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Rev Soc Bras Med Trop. 2014 Nov-Dec;47(6):677-83. doi: 10.1590/0037-8682-0246-2014.
Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are emergent arthropod-borne viruses that produce outbreaks of acute febrile illness with arthropathy. Despite their different continental origins, CHIKV and MAYV are closely related and are components of the Semliki Forest Complex of the Alphavirus (Togaviridae). MAYV and, more recently, CHIKV, which are both transmitted by Aedes mosquitoes, have resulted in severe public health problems in the Americas, including Brazil. In this review, we present aspects of the pathogenesis, clinical presentation and treatment of febrile illnesses produced by CHIKV and MAYV. We also discuss the epidemiological aspects and effects related to the prophylaxis of infections by both viruses.
基孔肯雅病毒（CHIKV）和马亚罗病毒（MAYV）是新出现的节肢动物传播病毒，可引发伴有关节病的急性发热性疾病暴发。尽管它们起源于不同的大陆，但CHIKV和MAYV密切相关，并且是甲病毒属（披膜病毒科）的塞姆利基森林病毒复合体的组成部分。MAYV以及最近的CHIKV均由伊蚊传播，在包括巴西在内的美洲地区引发了严重的公共卫生问题。在本综述中，我们介绍了由CHIKV和MAYV引起的发热性疾病的发病机制、临床表现和治疗方面。我们还讨论了与这两种病毒感染预防相关的流行病学方面及影响。
