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合并症对髋部骨折手术后6个月内再入院及死亡率的影响。

Impact of comorbidity on 6-month hospital readmission and mortality after hip fracture surgery.

作者信息

Härstedt Maria, Rogmark Cecilia, Sutton Richard, Melander Olle, Fedorowski Artur

机构信息

Department of Internal Medicine, Skåne University Hospital, SE 205-02 Malmö, Sweden; Department of Clinical Sciences, Lund University, Clinical Research Centre, Skåne University Hospital, SE 205-02 Malmö, Sweden.

Department of Orthopaedics, Skåne University Hospital, SE 205-02 Malmö, Sweden.

出版信息

Injury. 2015 Apr;46(4):713-8. doi: 10.1016/j.injury.2014.12.024. Epub 2014 Dec 30.

Abstract

OBJECTIVES

Impact of comorbidity on risk of readmission and death after hip fracture surgery has not been sufficiently explored. We planned to investigate the role of common diseases in predicting adverse events during recovery after hip surgery.

PATIENTS AND METHODS

We prospectively evaluated 272 consecutive patients (age, 82.6±8.9 years; 196 females, 72.1%) who underwent acute surgery for hip fracture at a regional university hospital. Baseline comorbidity and hospital stay were analysed. Number, timing and reasons for readmissions as well as mortality within 6 months after hospital discharge were recorded. An age- and sex-adjusted logistic regression model was applied to assess relations between comorbidity and relative risk of rehospitalisation or death.

RESULTS

Hypertension (44%), cognitive disorders (26%), and ischaemic heart disease (19%) were the most common comorbidities. The mean length-of-postoperative-stay was 12.7±7.9 days. Eighty-six patients (32%) were readmitted to hospital within 6 months from initial discharge and 36 patients (13%) died during that period. Increased risk of readmission was associated with hypertension (odds ratio (OR): 2.0, 95%CI, 1.2-1.9, p=0.009), and pacemaker treatment (OR: 6.6, 95%CI, 1.7-26.3, p=0.007), while there was a tendency towards readmission among men with prostate disease (OR: 5.0, 95%CI, 0.9-27.2, p=0.06). In contrast, mortality was predicted by ischaemic heart disease (OR: 2.2, 95%CI, 1.0-4.9, p=0.05), and malignancy (OR: 2.5, 95%CI, 1.1-5.7, p=0.04).

CONCLUSIONS

Common comorbidities are associated with higher risk of rehospitalisation and mortality following hip fracture surgery in the elderly. This information may be useful in postoperative risk assessment and prevention of negative outcomes.

摘要

目的

合并症对髋部骨折手术后再入院风险和死亡风险的影响尚未得到充分研究。我们计划调查常见疾病在预测髋部手术后恢复期间不良事件中的作用。

患者与方法

我们前瞻性评估了一家地区大学医院连续接受髋部骨折急性手术的272例患者(年龄82.6±8.9岁;女性196例,占72.1%)。分析了基线合并症和住院时间。记录了再入院的次数、时间和原因以及出院后6个月内的死亡率。应用年龄和性别调整的逻辑回归模型评估合并症与再住院或死亡相对风险之间的关系。

结果

高血压(44%)、认知障碍(26%)和缺血性心脏病(19%)是最常见的合并症。术后平均住院时间为12.7±7.9天。86例患者(32%)在首次出院后6个月内再次入院,36例患者(13%)在此期间死亡。再入院风险增加与高血压(比值比(OR):2.0,95%置信区间,1.2 - 1.9,p = 0.009)和起搏器治疗(OR:6.6,95%置信区间,1.7 - 26.3,p = 0.007)相关,而患有前列腺疾病的男性有再入院倾向(OR:5.0,95%置信区间,0.9 - 27.2,p = 0.06)。相比之下,缺血性心脏病(OR:2.2,95%置信区间,1.0 - 4.9,p = 0.05)和恶性肿瘤(OR:2.5,95%置信区间,1.1 - 5.7,p = 0.04)可预测死亡率。

结论

常见合并症与老年髋部骨折手术后再住院和死亡风险较高相关。这些信息可能有助于术后风险评估和预防不良结局。

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